User profiles for Zachary Pennington

Zach Pennington

- Verified email at mayo.edu - Cited by 2514

Zachary T Pennington

- Verified email at mssm.edu - Cited by 1297

Dissecting impulsivity and its relationships to drug addictions

…, SM Groman, AS James, ZT Pennington - Annals of the New …, 2014 - Wiley Online Library
Addictions are often characterized as forms of impulsive behavior. That said, it is often noted
that impulsivity is a multidimensional construct, spanning several psychological domains. …

Basolateral amygdala to orbitofrontal cortex projections enable cue-triggered reward expectations

NT Lichtenberg, ZT Pennington, SM Holley… - Journal of …, 2017 - Soc Neuroscience
To make an appropriate decision, one must anticipate potential future rewarding events,
even when they are not readily observable. These expectations are generated by using …

Breakdown of spatial coding and interneuron synchronization in epileptic mice

…, I Mollinedo-Gajate, L Chen, ZT Pennington… - Nature …, 2020 - nature.com
Temporal lobe epilepsy causes severe cognitive deficits, but the circuit mechanisms remain
unknown. Interneuron death and reorganization during epileptogenesis may disrupt the …

[HTML][HTML] ezTrack: An open-source video analysis pipeline for the investigation of animal behavior

ZT Pennington, Z Dong, Y Feng, LM Vetere… - Scientific reports, 2019 - nature.com
Tracking animal behavior by video is one of the most common tasks in the life sciences.
Although commercial software exists for executing this task, they often present enormous cost to …

Reward, interrupted: Inhibitory control and its relevance to addictions

JD Jentsch, ZT Pennington - Neuropharmacology, 2014 - Elsevier
There are broad individual differences in the ability to voluntarily and effortfully suppress
motivated, reward-seeking behaviors, and this review presents the hypothesis that these …

A return to the psychiatric dark ages with a two-system framework for fear

MS Fanselow, ZT Pennington - Behaviour research and therapy, 2018 - Elsevier
The past several decades has seen considerable progress in our understanding of the
neurobiology of fear and anxiety. These advancements were spurred on by envisioning fear as …

Learning curves in robot-assisted spine surgery: a systematic review and proposal of application to residency curricula

Z Pennington, BF Judy, HM Zakaria, N Lakomkin… - Neurosurgical …, 2022 - thejns.org
OBJECTIVE Spine robots have seen increased utilization over the past half decade with the
introduction of multiple new systems. Market research expects this expansion to continue …

The danger of LeDoux and Pine's two-system framework for fear

MS Fanselow, ZT Pennington - American Journal of …, 2017 - Am Psychiatric Assoc
… physiology, Fanselow and Pennington argue that clinical data … Fanselow and Pennington
argue that physiological and … Fanselow and Pennington also suggest that our framework …

Minian, an open-source miniscope analysis pipeline

Z Dong, W Mau, Y Feng, ZT Pennington, L Chen… - Elife, 2022 - elifesciences.org
Miniature microscopes have gained considerable traction for in vivo calcium imaging in
freely behaving animals. However, extracting calcium signals from raw videos is a …

The medial orbitofrontal cortex–basolateral amygdala circuit regulates the influence of reward cues on adaptive behavior and choice

…, L Sepe-Forrest, ZT Pennington… - Journal of …, 2021 - Soc Neuroscience
Adaptive reward-related decision making requires accurate prospective consideration of the
specific outcome of each option and its current desirability. Often this information must be …