[HTML][HTML] Intervertebral disc degeneration—Current therapeutic options and challenges

A Samanta, T Lufkin, P Kraus - Frontiers in Public Health, 2023 - frontiersin.org
Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …

Fusion rate for stand-alone lateral lumbar interbody fusion: a systematic review

MK Manzur, ME Steinhaus, SS Virk, B Jivanelli… - The Spine Journal, 2020 - Elsevier
BACKGROUND Lateral lumbar interbody fusion (LLIF) is used to treat multiple conditions,
including spondylolisthesis, degenerative disc disorders, adjacent segment disease, and …

Laminoplasty—an underutilized procedure for cervical spondylotic myelopathy

WY Lopez, BC Goh, S Upadhyaya, C Ziino… - The Spine Journal, 2021 - Elsevier
ABSTRACT BACKGROUND CONTENT Cervical laminoplasty (LP) and laminectomy and
fusion (LF) are commonly used surgical techniques for cervical spondylotic myelopathy …

Promotion of higher rates of early fusion using activated titanium versus polyetheretherketone cages in adults undergoing 1-and 2-level transforaminal lumbar …

N Toop, J Dhaliwal, CS Gifford, D Gibbs… - … of Neurosurgery: Spine, 2023 - thejns.org
OBJECTIVE There is ongoing debate on the relative benefits and drawbacks of
polyetheretherketone (PEEK) versus titanium (Ti) in generating a bone-to-implant surface …

Development and validation of cervical prediction models for patient-reported outcomes at 1 year after cervical spine surgery for radiculopathy and myelopathy

KR Archer, M Bydon, I Khan, H Nian, JS Pennings… - Spine, 2020 - journals.lww.com
Study Design. Retrospective analysis of prospectively collected registry data. Objective. To
develop and validate prediction models for 12-month patient-reported outcomes of disability …

Longitudinal trends of patient demographics and morbidity of different approaches in lumbar interbody fusion: an analysis using the American College of Surgeons …

L Oezel, I Okano, AP Hughes, M Sarin, J Shue… - World Neurosurgery, 2022 - Elsevier
Objective The aims of this study were to determine the time trend of demographics,
complications, and outcomes for patients undergoing posterior lumbar interbody …

Baseline risk factors for prolonged opioid use following spine surgery: Systematic review and meta-analysis

S Mohan, CP Lynch, EDK Cha, KC Jacob, MR Patel… - World Neurosurgery, 2022 - Elsevier
Objective To conduct a comprehensive systematic review and meta-analysis of current
retrospective cohort studies to identify significant preoperative risk factors for prolonged …

[HTML][HTML] Benzo [a] pyrene injures BMP2-induced osteogenic differentiation of mesenchymal stem cells through AhR reducing BMPRII

L An, Q Shi, M Fan, G Huang, M Zhu, M Zhang… - Ecotoxicology and …, 2020 - Elsevier
Abstract Benzo [a] pyrene (BaP), a polycyclic aromatic hydrocarbons (PAH) of environmental
pollutants, is one of the main ingredients in cigarettes and an agonist of the aryl hydrocarbon …

The importance of smoking in orthopedic surgery

EC Rodriguez-Merchan - Hospital Practice, 2018 - Taylor & Francis
Introduction: Tobacco use is related to augmented morbidity and mortality. People who
smoke heavily before orthopedic surgery may have more nonmedical complications than …

The effects of sildenafil and/or nitroglycerin on random-pattern skin flaps after nicotine application in rats

MA Ellabban, IOA Fattah, GA Kader, OS Eldeen… - Scientific Reports, 2020 - nature.com
Smoking aggravates skin necrosis as a complication of random-pattern flap ischaemia.
Sildenafil and nitroglycerin (NTG) are vasodilator agents that may affect skin flap survival …