Background: The aim of this review is to investigate current uses of fibrinogen as a tool to
reduce operative and postoperative blood loss in different surgical fields especially …

Background Spinal surgeries often have a high risk of hemorrhage during and after surgery,
thus most patients require blood transfusions and blood products. Fibrinogen is used in …

Background Low level of fibrinogen is a risk factor of perioperative bleeding, which is a
major complication in surgical patients. However, the safety and efficacy of fibrinogen …

Purpose Spine surgery, particularly reconstructive surgery, can be associated with
significant blood loss, and blood transfusion. Antifibrinolytic agents are used routinely to …

Purpose Spine surgery is usually associated with large amount of blood loss and blood
transfusion. Excessive blood loss may cause hypotension, inadequate oxygenation of …

Introduction: Fibrin glue is widely used in spine surgery. Nevertheless, no report has
demonstrated the feasibility of completely autologous fibrin glue (CAFG) in spine surgery …

Background: Spinal surgeries are frequently complicated with high rate of intra-and post-
operative hemorrhage. It is shown that the serum fibrinogen level is a pivotal factor in …

Method The papers used in this review were searched in BioMed Central, PubMed,
Embase, and the Cochrane Central Register of Clinical Trial by two investigators. The full …

Background: Antifibrinolytic agents have been shown to decrease the blood loss associated
with major orthopaedic surgical procedures. Spine surgery, particularly procedures …

Study Design. Systematic review. Objective. To determine the definition and incidence of
significant hemorrhage in adult spine fusion surgery, and to assess whether measures to …