Background: Guidelines do not suggest the routine use of methylprednisolone (MP) in
patients with acute traumatic spinal cord injury (SCI). We tested the hypothesis regarding …

Purpose The controversial practice of methylprednisolone (MP) application in acute spinal
cord injury (ASCI) is gradually decreasing. This is a survey study designed to assess the …

Background: A systematic review of the evidence pertaining to methylprednisolone infusion
following acute spinal cord injury was conducted in order to address the persistent confusion …

BACKGROUND CONTEXT: Methylprednisolone has evolved during the 1990s, through the
results obtained from the National Acute Spinal Cord Injury Studies NASCIS II and III, as a …

A 26-year-old man with no significant medical history is found lying unconscious beside an
overturned car. He was taken to a local hospital by paramedics. In the emergency …

BACKGROUND: Methylprednisolone has been used for the treatment of acute spinal cord
injury but there is a dispute about the efficacy and safety of methylprednisolon. OBJECTIVE …

Study design Randomized clinical trial. Objectives To evaluate the safety and effectiveness
of intrathecal methyl-prednisolone compared to intravenous methyl-prednisolone in acute …

High doses of methylprednisolone (MPSS) came into use as part of a therapeutic protocol
for acute spinal cord injuries following the published results from the NASCIS II study in …

Methods Retrospective cohort study of patients admitted to the intensive care unit (ICU)
between 1997 and 2007 with a diagnosis of spinal cord injury due to trauma. The patients …

Objectives. Randomized trials are widely recognized as providing the most reliable
evidence for assessing efficacy and safety of therapeutic interventions. This evidence base …