This International Society for the Advancement of Spine Surgery statement has been
generated to respond to growing requests for background, supporting literature and …

Introduction Low back pain impacts most people throughout the course of their lives and
contributes significantly to the global burden of disease. In some patients, symptoms resolve …

Results Sub-analysis by non-surgical spine pathologies demonstrates that improvements in
pain (VAS), disability (ODI) and quality of life (EQ-5D) are equally substantial and durable …

In this review, we present a comprehensive clinical approach to restorative neurostimulation,
a novel form of stimulation for refractory chronic mechanical low back pain, targeting …

Objective This study aims to evaluate the usefulness of peripheral nerve stimulation as a
treatment option for patients with chronic low back pain. Materials and Methods More than …

Introduction Data on the Medicare-aged population show that older patients are major
consumers of low back pain (LBP) interventions. An effective approach for patients with …

Objectives The purpose of the ongoing follow-up of ReActiv8-A clinical trial is to document
the longitudinal benefits of episodic stimulation of the dorsal ramus medial branch and …

Background Neuromuscular instability of the lumbar spine resulting from impaired motor
control and degeneration of the multifidus muscle is a known root cause of refractory chronic …

Introduction Chronic low back pain (CLBP) is the leading cause of years lived with disability
globally. The role of restorative neurostimulation in the treatment of patients with refractory …

Introduction Mechanical chronic low back pain is often associated with impaired
neuromuscular control of the lumbar multifidus muscles, the most important stabilizers of the …