The effects of topical vancomycin on mesenchymal stem cells: more may not be better
S Chu, N Chen, ABC Dang, AC Kuo… - International Journal of …, 2017 - ijssurgery.com
Background The use of topical vancomycin is increasingly popular in spine surgery. Large
retrospective reviews suggest that topical vancomycin provides a cost-effective decrease in …
retrospective reviews suggest that topical vancomycin provides a cost-effective decrease in …
[HTML][HTML] The inhibitory effects of vancomycin on rat bone marrow–derived mesenchymal stem cell differentiation
K Hanson, C Isder, K Shogren, AL Mikula, L Lu… - … of Neurosurgery: Spine, 2021 - thejns.org
OBJECTIVE The use of intrawound vancomycin powder in spine surgery has been shown to
decrease the rate of surgical site infections; however, the optimal dose is unknown. High …
decrease the rate of surgical site infections; however, the optimal dose is unknown. High …
Does intrawound application of vancomycin influence bone healing in spinal surgery?
C Eder, S Schenk, J Trifinopoulos, B Külekci… - European Spine …, 2016 - Springer
Purpose Surgical site infections represent a major complication of spinal surgery. The
application of lyophilised vancomycin into the wound is reported to significantly decrease …
application of lyophilised vancomycin into the wound is reported to significantly decrease …
Effect of intra‐wound vancomycin for spinal surgery: a systematic review and meta‐analysis
L Xie, J Zhu, M Yang, C Yang, S Luo, Y Xie… - Orthopaedic …, 2017 - Wiley Online Library
Intra‐site prophylactic vancomycin in spine surgery is an effective method of decreasing the
incidence of postsurgical wound infection. However, there are differences in the prophylactic …
incidence of postsurgical wound infection. However, there are differences in the prophylactic …
Use of intrawound vancomycin powder against postoperative infection after spine surgery
H Takahashi, Y Iida, Y Yokoyama… - Spine Surgery and …, 2018 - jstage.jst.go.jp
Local application of vancomycin has recently become widely used in spine surgery.
However, local application is not included in the indication and has not been approved by …
However, local application is not included in the indication and has not been approved by …
Vancomycin is toxic to human chondrocytes in vitro
E Röhner, T Zippelius, S Böhle, S Rohe… - Archives of Orthopaedic …, 2021 - Springer
Introduction Vancomycin powder (VP) is a well-established topical antibiotic used in spinal
surgery to prevent surgical site infections. More recently its extension to hip and knee …
surgery to prevent surgical site infections. More recently its extension to hip and knee …
[HTML][HTML] Do dose-dependent microbial changes occur during spine surgery as a result of applying intrawound vancomycin powder?: a systematic literature review
L Xie, J Zhu, S Luo, Y Xie, D Pu - Asian Spine Journal, 2018 - ncbi.nlm.nih.gov
We analyzed dose-dependent effects of vancomycin on wound infection bacteria and
investigated the relationship between dose and microbial imbalances in patients treated …
investigated the relationship between dose and microbial imbalances in patients treated …
The effect of vancomycin and gentamicin antibiotics on human osteoblast proliferation, metabolic function, and bone mineralization
Study Design. The present study investigates the effect of vancomycin and gentamicin
antibiotics on primary human osteoblasts. Osteoblasts were incubated with vancomycin …
antibiotics on primary human osteoblasts. Osteoblasts were incubated with vancomycin …
Selection pressures of vancomycin powder use in spine surgery: a meta-analysis
A Gande, A Rosinski, T Cunningham, N Bhatia… - The Spine Journal, 2019 - Elsevier
BACKGROUND CONTEXT Surgical site infection (SSI) is a serious and costly complication
of spine surgery. Many surgeons apply vancomycin powder to the surgical wound to prevent …
of spine surgery. Many surgeons apply vancomycin powder to the surgical wound to prevent …
Intraoperative vancomycin use in spinal surgery: single institution experience and microbial trends
GM Ghobrial, V Thakkar, E Andrews, M Lang, A Chitale… - Spine, 2014 - journals.lww.com
Study Design. Retrospective case series. Objective. To demonstrate the microbial trends of
spinal surgical site infections in patients who had previously received crystallized …
spinal surgical site infections in patients who had previously received crystallized …