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Research ArticleOther & Special Categories

Safety and Efficacy of Balloon Kyphoplasty for Vertebral Fractures With Posterior Wall Disruption

Jennifer L. Perez, Alp Ozpinar, Nitin Agarwal, Emily Hacker, Nima Alan and Peter C. Gerszten
International Journal of Spine Surgery April 2021, 8046; DOI: https://doi.org/10.14444/8046
Jennifer L. Perez
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
PHD
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Alp Ozpinar
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
MD
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Nitin Agarwal
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
MD
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Emily Hacker
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
BS
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Nima Alan
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
MD
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Peter C. Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
MD, MPH
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ABSTRACT

Background Percutaneous balloon kyphoplasty (BK) is widely accepted as both a safe and effective method for the treatment of symptomatic benign vertebral compression fractures (VCFs) of the thoracic and lumbar spines. A disruption in the posterior wall of the affected vertebra is often considered to be a relative or an absolute contraindication to BK. This study was performed to determine the safety as well as the efficacy of BK for vertebral body compression fractures associated with posterior wall disruption.

Methods This was a retrospective, nonrandomized clinical cohort investigation of patients with VCF and posterior wall disruption treated with BK between 2010 and 2018. All cases were performed using a bipedicular technique. Each case was examined for cement leakage, anterior vertebral body height restoration, improvement in pain (determined by VAS) from baseline and 6-week postprocedure, and clinical sequelae from cement leakage.

Results Ninety-eight consecutive patients with 157 VCF levels who underwent BK were evaluated. There was a significant improvement in anterior vertebral height, vertebral wedge angle, and local kyphotic angle in all cases. The mean preoperative VAS improved from 8.7 preprocedure to 2.5 postprocedure (P = .001). There were 14 (9%) cases with asymptomatic cement leakage outside of the vertebral body, and no patients experienced postprocedure neurological symptoms at the 6-week follow up.

Conclusions BK in the setting of posterior wall disruption was found to be a safe and highly effective treatment for patients with benign compression fractures. Posterior wall disruption should not be considered an absolute contraindication to BK.

  • cement augmentation
  • osteoporosis
  • spine fracture
  • vertebral compression fracture
  • vertebroplasty

Footnotes

  • Disclosures and COI: Data from this study was presented at the 35th Annual Meeting of the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves, Spine Summit, Miami, FL, March 14–17, 2019. The authors received no funding for this study and report no conflicts of interest.

  • This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery. Copyright © 2021 ISASS
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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Safety and Efficacy of Balloon Kyphoplasty for Vertebral Fractures With Posterior Wall Disruption
Jennifer L. Perez, Alp Ozpinar, Nitin Agarwal, Emily Hacker, Nima Alan, Peter C. Gerszten
International Journal of Spine Surgery Apr 2021, 8046; DOI: 10.14444/8046

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Safety and Efficacy of Balloon Kyphoplasty for Vertebral Fractures With Posterior Wall Disruption
Jennifer L. Perez, Alp Ozpinar, Nitin Agarwal, Emily Hacker, Nima Alan, Peter C. Gerszten
International Journal of Spine Surgery Apr 2021, 8046; DOI: 10.14444/8046
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Keywords

  • Cement augmentation
  • osteoporosis
  • spine fracture
  • vertebral compression fracture
  • vertebroplasty

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