Tranexamic Acid Reduced the Percent of Total Blood Volume Lost During Adolescent Idiopathic Scoliosis Surgery

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Table 2

Characteristics and Baseline Hematologic Status of Patients who Underwent Posterior Spine Fusion for Adolescent Idiopathic Scoliosis.

Patients	Tranexamic acid N=18 Mean (sd)	No tranexamic acid N=18 Mean (sd)	P value
Females n (%)	16 (88.9)	15 (83.3)	0.63
Age (yrs.)	16.1 (3.1)	15.2 (3.4)	0.44
Body mass index (kg/m²)	22.2 (5.2)	20.2 (3.3)	0.19
Preoperative hemoglobin (g/ dL)	13.9 (1.3)	13.9 (1.1)	1.00
Estimated total blood volume (L)¹⁴	3.80 (0.89)	3.38 (0.48)	0.15

N: number, Yrs: years,kg/m²: kilograms per meter squared, g/dL: grams per deciliter, L: Liter.

Table 3

Operative Factors and Blood-related Outcomes of Patients who Underwent Posterior Spine Fusion for Adolescent Idiopathic Scoliosis.

	Tranexamic acid n=18		No tranexamic acid n=18
Variable	Mean(sd)	Median [range]	Mean(sd)	Median [range]	Pvalue
Number of levels fused	10.5 (2.2)	11.0	9.6(2.0)	10.0	0.21
Number of osteotomies	1.6 (2.5)	[0-8]	0.9 (1.6)	[0-5]	0.34
Duration of operation (hours)	6.1(1.1)	6.0	6.1(1.2)	6.3	1.00
Estimated blood loss (ml)	474 (382)	285	583 (316)	500	0.12
Est. blood loss/level fused (ml)	44 (31)	33	61(33)	46	0.06
Percent total blood volume lost	12.1(8.8)	8.23	17.3 (8.8)	14.30	0.03
Percent TBV lost/level fused	1.1(0.7)	1.0	1.8 (1.0)	1.0	tf3-10.05