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Research ArticleLumbar Spine

The Diagnostic Value of Magnetic Resonance Imaging in Identifying Unsuspected Malignancy in Patients Undergoing Percutaneous Vertebral Augmentation for Vertebral Compression Fractures

CHEW ZHIHONG, CHENG SHENG DA JOWELL, SYED AFTAB, SEANG BENG TAN, CHANG MING GUO, JOHN CHEN LI TAT, POH LING FONG, WILLIAM YEO and MASHFIQUL A. SIDDIQUI
International Journal of Spine Surgery October 2019, 13 (5) 464-469; DOI: https://doi.org/10.14444/6061
CHEW ZHIHONG
1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore
MD, MRCS
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CHENG SHENG DA JOWELL
2Duke-NUS Medical School, Singapore
BENG
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SYED AFTAB
3Department of Diagnostic Radiology, Singapore General Hospital, Singapore
MD
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SEANG BENG TAN
1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore
MBBS MMED
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CHANG MING GUO
1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore
MBBS, MMED (SURG)
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JOHN CHEN LI TAT
1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore
MBBS (NUI), BAO
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POH LING FONG
1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore
MBBS (SPORE), MMED (ORTHO)
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WILLIAM YEO
1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore
BAPPSC, MPHYT
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MASHFIQUL A. SIDDIQUI
1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore
MBBS, MRCS (SURG), MMED (ORTHO)
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    Figure 1

    Flow chart of results.

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    Figure 2

    Percentage of vertebral compression fractures (VCFs) secondary to malignancy for patients who underwent percutaneous vertebral augmentation procedures (PVAPs). The < 60 years age group had the largest percentage of VCF secondary to malignancy, of 40%, followed by 19.8%, 4.8%, and 2.2% for 60 to 69, 70 to 79, and > 80 years age groups, respectively.

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    Figure 3

    (A) Sagittal T1W; (B) sagittal T1FS + contrast; (C) axial T2W at L1 level; (D) axial T1FS + contrast at L1 level. There is a T1 hypointense lesion demonstrating contrast enhancement involving almost the entire L1 vertebral body in a patient with background breast cancer. Furthermore there is enhancement of the paravertebral soft tissue at this level suspicious for extraosseous component (indicated with an arrow). Note L5 is sacralised.

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    Figure 4

    (A) Sagittal T1W; (B) T1W FS with contrast; (C) axial T2W at T12; (D) axial T1 FS with contrast at T12. MRI thoracic spine of a patient with nonpathological grade 3 compression fracture of T12 vertebra status-post vertebroplasty (low signal indicated by arrow). Compare the relatively normal T1 bone marrow signal and lack of contrast enhancement and spinal canal involvement with prior figure of a patient with spinal metastasis.

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    Figure 5

    (A) Sagittal T1W; (B) axial T1W at L1; (C) sagittal STIR sequence; (D) axial T2W at L1. MRI lumbar spine of patient with unsuspected malignancy that showed no suspicious features of malignancy.

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International Journal of Spine Surgery
Vol. 13, Issue 5
1 Oct 2019
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The Diagnostic Value of Magnetic Resonance Imaging in Identifying Unsuspected Malignancy in Patients Undergoing Percutaneous Vertebral Augmentation for Vertebral Compression Fractures
CHEW ZHIHONG, CHENG SHENG DA JOWELL, SYED AFTAB, SEANG BENG TAN, CHANG MING GUO, JOHN CHEN LI TAT, POH LING FONG, WILLIAM YEO, MASHFIQUL A. SIDDIQUI
International Journal of Spine Surgery Oct 2019, 13 (5) 464-469; DOI: 10.14444/6061

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The Diagnostic Value of Magnetic Resonance Imaging in Identifying Unsuspected Malignancy in Patients Undergoing Percutaneous Vertebral Augmentation for Vertebral Compression Fractures
CHEW ZHIHONG, CHENG SHENG DA JOWELL, SYED AFTAB, SEANG BENG TAN, CHANG MING GUO, JOHN CHEN LI TAT, POH LING FONG, WILLIAM YEO, MASHFIQUL A. SIDDIQUI
International Journal of Spine Surgery Oct 2019, 13 (5) 464-469; DOI: 10.14444/6061
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