Skip to main content

Main menu

  • Home
  • Content
    • Current Issue
    • Advance Online Publication
    • Archive
  • About Us
    • About ISASS
    • About the Journal
    • Author Instructions
    • Editorial Board
    • Reviewer Guidelines & Publication Criteria
  • More
    • Advertise
    • Subscribe
    • Alerts
    • Feedback
  • Join Us
  • Reprints & Permissions
  • Sponsored Content
  • Other Publications
    • ijss

User menu

  • My alerts

Search

  • Advanced search
International Journal of Spine Surgery
  • My alerts
International Journal of Spine Surgery

Advanced Search

  • Home
  • Content
    • Current Issue
    • Advance Online Publication
    • Archive
  • About Us
    • About ISASS
    • About the Journal
    • Author Instructions
    • Editorial Board
    • Reviewer Guidelines & Publication Criteria
  • More
    • Advertise
    • Subscribe
    • Alerts
    • Feedback
  • Join Us
  • Reprints & Permissions
  • Sponsored Content
  • Follow ijss on Twitter
  • Visit ijss on Facebook
Research ArticleBiologics

A Comparative Evaluation of Commercially Available Cell-Based Allografts in a Rat Spinal Fusion Model

BRIAN JOHNSTONE, NIANLI ZHANG, ERIK I. WALDORFF, ERIC SEMLER, ANOUSKA DASGUPTA, MARCEL BETSCH, PAOLO PUNSALAN, HOLLY CHO, JAMES T. RYABY and JUNG YOO
International Journal of Spine Surgery April 2020, 14 (2) 213-221; DOI: https://doi.org/10.14444/7026
BRIAN JOHNSTONE
1Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, Oregon
PHD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: johnstob@ohsu.edu nianlizhang@orthofix.com
NIANLI ZHANG
2Orthofix Medical Inc, Lewisville, Texas
PHD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: johnstob@ohsu.edu nianlizhang@orthofix.com
ERIK I. WALDORFF
2Orthofix Medical Inc, Lewisville, Texas
PHD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
ERIC SEMLER
3MTF Biologics, Edison, New Jersey
PHD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
ANOUSKA DASGUPTA
3MTF Biologics, Edison, New Jersey
PHD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
MARCEL BETSCH
1Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, Oregon
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
PAOLO PUNSALAN
1Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, Oregon
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
HOLLY CHO
1Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, Oregon
MS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
JAMES T. RYABY
2Orthofix Medical Inc, Lewisville, Texas
PHD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
JUNG YOO
1Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, Oregon
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Figure 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1

    Radiographs and micro-CT 3-dimensional reconstructions of Osteocel Plus, Trinity Evolution, and Trinity ELITE implants immediately after implantation (day 0) and at 6 weeks postimplantation (day 42).

  • Figure 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2

    Radiographs of (a) syngeneic bone, (b) Osteocel Plus, (c) Trinity Evolution, and (d) Trinity ELITE allografts 6 weeks postimplantation in the athymic rat lumbar spine.

  • Figure 3
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 3

    Histology of (a) syngeneic bone (b) Osteocel Plus, (c) Trinity Evolution, and (d) Trinity ELITE allografts 6 weeks postimplantation in the athymic rat lumbar spine (toluidine blue–stained, paraffin-embedded sections).

  • Figure 4
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 4

    Semiquantitative histopathological scores for syngeneic bone, Osteocel Plus, Trinity Evolution, and Trinity ELITE allografts 6 weeks postimplantation in the athymic rat lumbar spine.

  • Figure 5
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 5

    Volume of fusion masses (mm3) for syngeneic bone, Osteocel Plus, Trinity Evolution, and Trinity ELITE allografts 6 weeks postimplantation in the athymic rat lumbar spine determined from micro-CT images.

Tables

  • Figures
  • Table 1
  • Table 2
PreviousNext
Back to top

In this issue

International Journal of Spine Surgery
Vol. 14, Issue 2
1 Apr 2020
  • Table of Contents
  • Index by author

Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on International Journal of Spine Surgery.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
A Comparative Evaluation of Commercially Available Cell-Based Allografts in a Rat Spinal Fusion Model
(Your Name) has sent you a message from International Journal of Spine Surgery
(Your Name) thought you would like to see the International Journal of Spine Surgery web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
A Comparative Evaluation of Commercially Available Cell-Based Allografts in a Rat Spinal Fusion Model
BRIAN JOHNSTONE, NIANLI ZHANG, ERIK I. WALDORFF, ERIC SEMLER, ANOUSKA DASGUPTA, MARCEL BETSCH, PAOLO PUNSALAN, HOLLY CHO, JAMES T. RYABY, JUNG YOO
International Journal of Spine Surgery Apr 2020, 14 (2) 213-221; DOI: 10.14444/7026

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
A Comparative Evaluation of Commercially Available Cell-Based Allografts in a Rat Spinal Fusion Model
BRIAN JOHNSTONE, NIANLI ZHANG, ERIK I. WALDORFF, ERIC SEMLER, ANOUSKA DASGUPTA, MARCEL BETSCH, PAOLO PUNSALAN, HOLLY CHO, JAMES T. RYABY, JUNG YOO
International Journal of Spine Surgery Apr 2020, 14 (2) 213-221; DOI: 10.14444/7026
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • ABSTRACT
    • INTRODUCTION
    • MATERIALS AND METHODS
    • STATISTICAL METHODS
    • RESULTS
    • DISCUSSION
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Allografts and Spinal Fusion
  • Google Scholar

More in this TOC Section

  • Stem Cells Therapy as a Treatment for Discogenic Low Back Pain: A Systematic Review
  • Does Bone Morphogenetic Protein Use Reduce Pseudarthrosis Rates in Single-Level Transforaminal Lumbar Interbody Fusion Surgeries?
  • Demineralized Bone Matrix and Fibers in Spinal Fusion
Show more Biologics

Similar Articles

Keywords

  • Posterolateral spine fusion
  • athymic rat
  • stem cells
  • allograft
  • Trinity Evolution
  • Trinity Elite
  • Osteocel Plus

Content

  • Current Issue
  • Latest Content
  • Archive

More Information

  • About IJSS
  • About ISASS
  • Privacy Policy

More

  • Subscribe
  • Alerts
  • Feedback

Other Services

  • Author Instructions
  • Join ISASS
  • Reprints & Permissions

© 2025 International Journal of Spine Surgery

International Journal of Spine Surgery Online ISSN: 2211-4599

Powered by HighWire