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Research ArticleLUMBAR ARTHROPLASTY
Open Access

Comparison of 2-Level Versus 1-Level Total Disc Replacement: Results From a Prospective FDA-Regulated Trial

Jack E. Zigler and Donna D. Ohnmeiss
International Journal of Spine Surgery January 2008, 2 (3) 140-144; DOI: https://doi.org/10.1016/SASJ-2008-0009-RR
Jack E. Zigler
aTexas Back Institute
MD
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Donna D. Ohnmeiss
bTexas Back Institute Research Foundation, Plano, Texas
DrMed
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    Figure 1

    The mean post-op VAS pain scores were significantly improved in both the 2-level and the 1-level groups (P < .05). There was no significant difference in the mean scores between the groups at any evaluation period (P > .15).

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    Figure 2

    The mean Oswestry scores improved significantly in both groups (P < .05). At none of the evaluation periods was there a significant difference in the mean scores between the two groups (P > .15).

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    Figure 3

    The mean satisfaction scores were very similar in the 1- and 2-level groups at all follow-up periods as assessed by a 0-10 point VAS with greater scores indicating greater satisfaction (P > .30).

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    Figure 4

    There was no significant difference in the proportional distribution of responses to the question,“Would you have the same treatment again?” (P > .25) when comparing 1- vs 2-level TDR.

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    Table 1

    Descriptives of the 1- and 2-Level TDR Subgroups

    1-Level (n = 54)2-Level (n = 32)Significance
    Gender P > .70
    Male53.7%53.1%
    Female46.3%46.9%
    Age (years): P < .05
    Mean38.043.9
    Range19-5728-59
    Levels Operated N/A
    L3-43.7%N/A
    L4-533.3%N/A
    L5-S163.0%N/A
    L3-4 & L4-5N/A12.5%
    L4-5 & L5-S1N/A87.5%
    Smoking P > .60
    Smoker35.2%34.4%
    Non-smoker64.8%65.6%
    Previous Surgery P > .60
    Yes33.3%37.5%
    No66.7%62.5%
    Insurance P > .60
    Private Insurance79.2%74.2%
    WC20.7%25.8%
    • The only significant difference was the mean age in the 2-level cases was significantly greater.

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    Table 2

    Perioperative Data for 1-Level and 2-Level Subgroups

    1-Level2-LevelSignificance
    Blood loss (ml)59.079.2.05 < P < .09
    Operative time (min)61.997.8 P < .001
    Length of hospitalization (days)1.892.44 P < .05
    • The mean blood loss, operative time and length of hospitalization were all less in single-level cases (P < .05; f-test).

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International Journal of Spine Surgery
Vol. 2, Issue 3
1 Jan 2008
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Comparison of 2-Level Versus 1-Level Total Disc Replacement: Results From a Prospective FDA-Regulated Trial
Jack E. Zigler, Donna D. Ohnmeiss
International Journal of Spine Surgery Jan 2008, 2 (3) 140-144; DOI: 10.1016/SASJ-2008-0009-RR

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Comparison of 2-Level Versus 1-Level Total Disc Replacement: Results From a Prospective FDA-Regulated Trial
Jack E. Zigler, Donna D. Ohnmeiss
International Journal of Spine Surgery Jan 2008, 2 (3) 140-144; DOI: 10.1016/SASJ-2008-0009-RR
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