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Research ArticleBiomechanics
Open Access

Measurement of occlusion of the spinal canal and intervertebral foramen by intervertebral disc bulge

Mathieu Cuchanski, Daniel Cook, Donald M. Whiting and Boyle C. Cheng
International Journal of Spine Surgery January 2011, 5 (1) 9-15; DOI: https://doi.org/10.1016/j.esas.2010.09.004
Mathieu Cuchanski
aDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA
BS
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  • For correspondence: mcuchanski@gmail.com
Daniel Cook
bDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA
cDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA
MS
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Donald M. Whiting
dDepartment of Neurosurgery, Drexel University College of Medicine, Pittsburgh, PA
MD
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Boyle C. Cheng
bDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA
cDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA
PhD
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  • Article
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Article Figures & Data

Figures

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  • Fig. 1
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    Fig. 1

    Measurement of spinal canal depth using eFilm Workstation.

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    Fig. 2

    Measurement of foraminal width using eFilm Workstation.

  • Fig. 3
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    Fig. 3

    Single FSU loaded in spine test machine. The arrows indicate the location of 4 of the 8 digitized points that were used to estimate the center of the disc.

  • Fig. 4
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    Fig. 4

    Transverse section of intervertebral disc showing location of 3 active LEDs and measurement of disc bulge.

Tables

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    Table 1

    Donor information of all spine specimens

    SpecimenAgeHeight (in)Weight (lb)SexDEXA (BMD)Cause of death
    C0805707067234FN/ACardiopulmonary arrest
    S0801086565108F0.813Respiratory failure, bacterial pneumonia
    S0804314873180F1.111Cardiac arrhythmia
    C0801336675177MN/ALung cancer
    S0804293465205F0.870Atherosclerotic coronary artery disease
    C0801726666145F0.700Cardiopulmonary arrest, intracerebral hemorrhage
    S0804046661110F0.639Respiratory failure
    • Abbreviations: DEXA, Dual Energy; X-Ray Absorptiometry; BMD, Bone Mineral Density; N/A, Not Available.

    • View popup
    Table 2

    DEXA summary

    LevelSpecimen
    C080570S080108S080431C080133S080429C080172S080404
    Region
     L1N/A0.7211.074N/A0.8470.6520.563
     L2N/A0.8301.126N/A0.8560.7460.653
     L3N/A0.8481.131N/A0.9010.7390.647
     L4N/A0.8391.108N/A0.8740.6610.678
    MeanN/A0.8131.111N/A0.8700.7000.639
    • Abbreviations: DEXA, Dual Energy; X-Ray Absorptiometry; N/A, Not Available.

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    Table 3

    Anterior column grading*

    LevelSpecimen
    C080133C080172C080570S080431S080404S080429S080108
    L1-20200001
    L2-30300001
    L3-41110000
    L4-51211000
    L5-S11011100
    • ↵* Graded on a scale from 0 to 4, where 0 indicates normal, 1 indicates mild degenerative disease, 2 indicates moderate degenerative disease, and 3 indicates severe degenerative disease.

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    Table 4

    Spinal canal depth and foraminal width measurements

    LevelPosterior (spinal canal depth) (mm)Posterolateral (foraminal width) (mm)**
    Specimen
     C080570L1-2246
     C080570L3-4235
     C080570L5-S1165
     S080404L1-2185
     S080404L3-4185
     S080404L5-S1165
     S080429L1-2256
     S080429L3-4226
     S080429L5-S1167
     S080108L1-2219
     S080108L3-4194
     S080108L5-S1134
     C080133L1-2259
     C080133L3-4208
     C080133L5-S1174
     S080431L1-2246
     S080431L3-4225
     S080431L5-S1215
     C080172L1-2195
     C080172L3-4174
     C080172L5-S1132
    Mean19 ± 45 ±2
    Maximum259
    Minimum132
    • View popup
    Table 5

    Summary of descriptive statistics by region and mode of load

    LevelPosterior (spinal canal depth)Posterolateral (foraminal width)
    250 N comp±2.5 Nm FE±2.5 Nm LB250 N comp±2.5 Nm FE±2.5 Nm LB
    Specimen
     C080570L1-21.13.60.64.410.78.2
     C080570L3-4
     C080570L5-S16.04.80.65.64.14.7
     S080404L1-21.43.12.35.95.824.4
     S080404L3-4
     S080404L5-S1
     S080429L1-22.01.61.810.112.513.7
     S080429L3-41.41.80.67.39.06.5
     S080429L5-S12.51.92.15.27.07.0
     S080108L1-21.11.10.83.04.44.7
     S080108L3-41.92.41.415.718.523.6
     S080108L5-S16.76.72.217.820.814.2
     C080133L1-22.31.51.83.95.79.0
     C080133L3-43.31.80.910.210.713.0
     C080133L5-S1
     S080431L1-20.61.61.03.75.34.5
     S080431L3-41.50.51.45.32.110.6
     S080431L5-S1
     C080172L1-21.41.61.45.87.813.9
     C080172L3-43.63.53.313.517.711.2
     C080172L5-S1
    Mean2.5 ± 1.92.5 ± 1.61.5 ± 0.87.8 ± 4.79.5 ± 5.711.3 ± 6.2
    Maximum6.76.73.317.820.824.4
    Minimum0.60.50.63.02.14.5
    • Abbreviations: comp, compression; FE, Flexion/Extension; LB, Lateral Bend.

    • Reported values are percent occlusion of specified region under 250-N axial compression, ± 2.5 Nm of flexion/extension, and ± 2.5 Nm of lateral bend.

    • View popup
    Table 6

    Repeated-measures ANOVA test results*

    Mean differenceSEP value†95% confidence interval for difference
    Lower boundUpper bound
    Posterior (spinal canal occlusion)
     1 and 3‡ 0.9730.456.051−0.0041.950
     2 and 10.0460.277.870−0.5480.640
     2 and 31.0190.421.0300.1161.922
    Posterolateral (intervertebral foramen occlusion)
     1 and 2−1.6370.580.014−2.880−0.393
     1 and 3−3.4581.389.026−6.439−0.478
     2 and 3−1.8221.619.280−5.2951.651
    • ↵* Mean difference is significant at the .05 level.

    • ↵† A least significant difference post hoc test was used to adjust for multiple comparisons.

    • ↵‡ A 1 indicates 250 N of axial compression; 2, ± 2.5 Nm of flexion/extension; and 3, ± 2.5 Nm of lateral bend.

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Measurement of occlusion of the spinal canal and intervertebral foramen by intervertebral disc bulge
Mathieu Cuchanski, Daniel Cook, Donald M. Whiting, Boyle C. Cheng
International Journal of Spine Surgery Jan 2011, 5 (1) 9-15; DOI: 10.1016/j.esas.2010.09.004

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Measurement of occlusion of the spinal canal and intervertebral foramen by intervertebral disc bulge
Mathieu Cuchanski, Daniel Cook, Donald M. Whiting, Boyle C. Cheng
International Journal of Spine Surgery Jan 2011, 5 (1) 9-15; DOI: 10.1016/j.esas.2010.09.004
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