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Research ArticleCervical Spine

Interim 1-Year Radiographic and Clinical Outcomes Following Anterior Cervical Discectomy and Fusion Using Hydroxyapatite-Infused Polyetheretherketone Interbody Cages

Michael J. Kelly, Bradley Gelfand, Kris Radcliff, Fred F. Mo, Brox A. Felix and S. Babak Kalantar
International Journal of Spine Surgery February 2024, 8585; DOI: https://doi.org/10.14444/8585
Michael J. Kelly
1 Hospital for Special Surgery, New York, NY, USA
MD
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  • For correspondence: mjk266@georgetown.edu
Bradley Gelfand
2 MedStar Georgetown University Hospital, Washington, DC, USA
MD
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Kris Radcliff
3 Spinal DISC Center, Somers Point, NJ, USA
MD
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Fred F. Mo
2 MedStar Georgetown University Hospital, Washington, DC, USA
MD
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Brox A. Felix
4 Princeton University, Undergraduate Student, Princeton, NJ, USA
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S. Babak Kalantar
2 MedStar Georgetown University Hospital, Washington, DC, USA
MD
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  • Figure 1
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    Figure 1

    Example of a 1-level anterior cervical discectomy and fusion using a hydroxyapatite-polyetheretherketone interbody cage at 1 year postoperatively. Note that the tantalum markers are useful for both intraoperative placement and postoperative radiographic evaluation.

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    Figure 2

    Bar plots for the radiographic outcome measures (left: angular range of motion; right: translational anteroposterior motion), including mean scores with SDs. Horizontal bars indicate post-hoc significant changes between preoperative and postoperative follow-up time points.

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    Figure 3

    Bar plots for the clinical outcome measures, including mean scores with SDs. Horizontal bars indicate post-hoc significant changes between time points.

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    Table 1

    Demographics and operative data of patient population.

    CharacteristicEntire CohortMenWomen
    Number of operated patients789383 (48.5%)406 (51.5%)
    Age at surgery, y, mean57.657.757.4
    Body mass index, mean29.930.329.6
    Current active smokers, %19.821.718.0
    Unemployed patients, %55.251.259.2
    Monosegmental patients, %34.234.234.2
    Bisegmental patients, %41.740.542.9
    ≥3 segmental patients, %24.125.322.9
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    Table 2

    PROMS at preoperative and standard postoperative periods.

    PROMPreoperative, Mean (SD, n)Postoperative, Mean (SD, n) P a
    6 wk3 mo6 mo12 mo
    NDI46.3 (19.8, 771)29.5 (20.3, 544)25.3 (20.8, 528)24.0 (21.6, 413)25.2 (22.3, 281)<0.01
    VAS neck64.2 (27.5, 770)30.7 (28.2, 541)28.1 (28.6, 519)27.1 (27.9, 413)28.6 (30.3, 278)<0.01
    VAS arm (right)42.6 (34.7, 766)18.9 (27.9, 541)18.4 (27.2, 519)17.4 (25.9, 413)20.4 (29.7, 277)<0.01
    VAS arm (left)41.1 (33.8, 768)18.0 (26.7, 541)17.0 (26.3, 519)18.5 (26.4, 413)20.8 (28.9, 277)<0.01
    • Abbreviations: NDI, Neck Disability Index; PROM, patient-reported outcome measure; VAS, visual analog scale.

    • ↵a One-way analysis of variance.

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    Table 3

    Analysis of patient satisfaction for all evaluated examination periods.

    How Satisfied Were You With Your Treatment?
    Examination periodSatisfiedSomewhat satisfiedSomewhat dissatisfiedDissatisfied
    6 wk (n = 569)82.6%15.1%2.1%0.2%
    3 mo (n = 551)81.8%13.8%3.5%0.9%
    6 mo (n = 433)83.4%13.4%2.5%0.7%
    12 mo (n = 287)81.2%13.9%3.8%1.0%
    Would You Have the Same Treatment Again?
    Examination periodDefinitely yesProbably yesProbably notDefinitely not
    6 wk (n = 569)67.5%26.2%4.8%1.6%
    3 mo (n = 551)69.3%22.7%5.6%2.2%
    6 mo (n = 433)68.1%25.2%5.3%1.4%
    12 mo (n = 287)64.8%27.5%5.9%1.7%
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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Interim 1-Year Radiographic and Clinical Outcomes Following Anterior Cervical Discectomy and Fusion Using Hydroxyapatite-Infused Polyetheretherketone Interbody Cages
Michael J. Kelly, Bradley Gelfand, Kris Radcliff, Fred F. Mo, Brox A. Felix, S. Babak Kalantar
International Journal of Spine Surgery Feb 2024, 8585; DOI: 10.14444/8585

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Interim 1-Year Radiographic and Clinical Outcomes Following Anterior Cervical Discectomy and Fusion Using Hydroxyapatite-Infused Polyetheretherketone Interbody Cages
Michael J. Kelly, Bradley Gelfand, Kris Radcliff, Fred F. Mo, Brox A. Felix, S. Babak Kalantar
International Journal of Spine Surgery Feb 2024, 8585; DOI: 10.14444/8585
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  • hydroxyapatite
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