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Research ArticleCervical Spine

Four-Level Cervical Disc Arthroplasty

Hsuan-Kan Chang, Chih-Chang Chang, Tsung-Hsi Tu, Yi-Hsuan Kuo, Ching-Lan Wu, Mei-Yin Yeh, Chao-Hung Kuo, Chin-Chu Ko, Li-Yu Fay, Wen-Cheng Huang and Jau-Ching Wu
International Journal of Spine Surgery May 2024, 8603; DOI: https://doi.org/10.14444/8603
Hsuan-Kan Chang
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
3 Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan
MD, PHD
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Chih-Chang Chang
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
MD
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Tsung-Hsi Tu
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
MD, PHD
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Yi-Hsuan Kuo
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
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Ching-Lan Wu
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
4 Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan
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  • For correspondence: michaelchang0903@gmail.com
Mei-Yin Yeh
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
5 Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
MD
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Chao-Hung Kuo
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
MD, PHD
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Chin-Chu Ko
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
5 Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
MD, PHD
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Li-Yu Fay
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
5 Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
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Wen-Cheng Huang
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
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Jau-Ching Wu
1 Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
2 College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
5 Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
MD, PHD
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  • Article
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  • Figure 1
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    Figure 1

    The preoperative magnetic resonance image of a 53-year-old woman who underwent 4-level CDA. Each level from C3-4 to C6-7 showed significant disc herniation and spinal stenosis that required surgery.

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    Figure 2

    Postoperative flexion/extension radiographs from the patient in Figure 1 at 24 months after surgery. The range of motion at each level was well preserved. Each artificial disc was demonstrated to be well-functioning.

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    Table 1

    Patients’ demographic data, radiographic outcomes, and complication profile.

    Patient Number N = 20
    Age, y56 ± 8
    Sex, M/F17/3
    Estimated blood loss, mL154 ± 27
    Follow-up, mo34 ± 20
    Subaxial C3-7 ROM, degrees
     Preoperation35 ± 8
     Final follow-up37 ± 10
     P value0.271
    Individual segmental ROM, degrees
     C3-49 ± 0.9
     C4-59 ± 0.9
     C5-69 ± 1.0
     C6-79 ± 1.0
    C2-7 Cobb angle, degrees
     Preoperation8 ± 11
     Postoperation12 ± 12
     P value0.114
    C2-7 sagittal vertical axis, cm
     Preoperation2.2 ± 1.3
     Postoperation2.3 ± 1.5
     P value0.804
    Complications
     Postoperation transient C5 radiculopathy2 (10%)
     Postoperation permanent C5 radiculopathy1 (5%)
     Transient dysphagia2 (10%)
     Poor wound healing1 (5%)
    • Abbreviation: ROM, range of motion.

    • Note: Values are presented as mean ± SD, n, or n (%).

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    Table 2

    Clinical outcome measures.

    Outcome MeasurePreoperationFinal Follow-up P value
    VAS of neck pain4.6 ± 4.01.3 ± 1.8 0.021
    VAS of arm pain4.3 ± 3.61.0 ± 1.7 0.026
    Neck Disability Index8.2 ± 7.43.9 ± 3.0 0.034
    Modified Japanese Orthopedic Association score13.8 ± 1.715.2 ± 1.3 0.041
    • Abbreviation: VAS, visual analog scale.

    • Note: Values are presented as mean ± SD. Boldface type indicates statistical significance.

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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Four-Level Cervical Disc Arthroplasty
Hsuan-Kan Chang, Chih-Chang Chang, Tsung-Hsi Tu, Yi-Hsuan Kuo, Ching-Lan Wu, Mei-Yin Yeh, Chao-Hung Kuo, Chin-Chu Ko, Li-Yu Fay, Wen-Cheng Huang, Jau-Ching Wu
International Journal of Spine Surgery May 2024, 8603; DOI: 10.14444/8603

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Four-Level Cervical Disc Arthroplasty
Hsuan-Kan Chang, Chih-Chang Chang, Tsung-Hsi Tu, Yi-Hsuan Kuo, Ching-Lan Wu, Mei-Yin Yeh, Chao-Hung Kuo, Chin-Chu Ko, Li-Yu Fay, Wen-Cheng Huang, Jau-Ching Wu
International Journal of Spine Surgery May 2024, 8603; DOI: 10.14444/8603
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Keywords

  • anterior cervical discectomy and fusion (ACDF)
  • cervical disc arthroplasty (CDA)
  • range of motion (ROM)
  • multi-level
  • four-level

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