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Research ArticleLumbar Spine

Mismatch Between Pelvic Incidence and Lumbar Lordosis After Personalized Interbody Fusion: The Importance of Preoperative Planning and Alignment in Degenerative Spine Diseases

Jahangir Asghar, Ashvin I. Patel, Joseph A. Osorio, Justin S. Smith, John Small, Jeffrey P. Mullin, Atman Desai, Michele Temple-Wong and Rodrigo J. Nicolau
International Journal of Spine Surgery August 2024, 8638; DOI: https://doi.org/10.14444/8638
Jahangir Asghar
1 Elite Spine Health and Wellness, Plantation, FL, USA
MD
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  • For correspondence: jasghar01@gmail.com
Ashvin I. Patel
2 Kennedy-White Orthopedic Center, Sarasota, FL, USA
MD
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Joseph A. Osorio
3 Department of Neurological Surgery, University of California, San Diego, CA, USA
MD, PHD
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Justin S. Smith
4 Department of Neurosurgery, University of Virginia, Charlottesville, VA, USA
MD, PHD
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John Small
5 Center for Spinal Disorders at Florida Orthopaedic Institute, Temple Terrace, FL, USA
MD
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Jeffrey P. Mullin
6 Department of Neurosurgery, University at Buffalo, Buffalo, NY, USA
MD
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Atman Desai
7 Department of Neurosurgery, Stanford University Hospital and Clinics, Stanford, CA, USA
MD
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Michele Temple-Wong
8 Carlsmed, Carlsbad, CA, USA
PHD
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Rodrigo J. Nicolau
8 Carlsmed, Carlsbad, CA, USA
MD
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    Figure 1

    Left: Among patients who were preoperatively aligned, there was no statistically significant difference in either the “preserved” or “worsened” groups between stock devices and personalized interbody devices. Right: Among patients who were preoperatively malaligned, there was a statistically significant increase in the “restored” and a statistically significant decrease in the “worsened” groups compared with stock devices (P < 0.05; stock device data from Leveque et al6).

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    Figure 2

    Changes in spinal alignment parameters for the entire cohort of 1- and 2-level fusion patients at pre- and postoperative time points, including lumbar lordosis (LL), pelvic incidence (PI), and the calculation of PI–LL mismatch. Comparison between personalized interbody devices (left) and stock interbody devices (right).

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    Table 1

    Radiographic information for the full sample.

    CharacteristicsPreoperativePostoperativePre- to Postoperative ChangeSignificance (P < 0.05)
    Lumbar lordosis, degrees, mean (SD; range)50.9 (12.4; 21–77)54.2 (13.5; 17–85)3.3 (8.2; –25–32)<0.001
    Pelvic incidence, degrees, mean (SD; range)57.5 (13.0; 33–88)58.4 (12.5; 37–88)0.9 (3.3; –10–11)0.002
    Spinopelvic alignment (PI–LL mismatch), degrees, mean (SD; range)6.6 (11.5; –18–32)4.2 (12.0; –29–42)–2.5 (8.6; –30–29)0.001
    Patients with spinopelvic malalignment (PI–LL mismatch ≥ 10°), n (%)52 (38.5)36 (26.7) 0.006
    • Abbreviations: LL, lumbar lordosis; PI, pelvic incidence.

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    Table 2

    Radiographic information separated into pre- and postoperative alignment categories.

    CharacteristicsDegrees, mean (SD; range)Significancea P < 0.005
    Preserved n = 76 (56.3%)Restored n = 23 (17.0%)Not Corrected n = 29 (21.5%)Worsened n = 7 (5.2%)
    Preoperative
     Lumbar lordosis55.0 (10.1; 30–76)45.1 (13.8; 21–73)44.7 (11.2; 26–62)50.3 (17.8; 24–77)<0.001
     Pelvic incidence54.0 (10.9; 36–83)61.4 (14.5; 41–88)64.7 (11.9; 42–83)53.3 (18.5; 33–85)<0.001
     Spinopelvic alignment (PI–LL)–1.0 (7.1; –18–10)16.3 (5.6; 10–30)20.0 (5.9; 11–32)3.0 (8.0; –13–9)<0.001
    Postoperative
     Lumbar lordosis58.3 (11.1; 37–85)56.3 (13.5; 29–81)45.3 (12.2; 17–62)39.9 (16.7; 22–71)<0.001
     Pelvic incidence55.4 (10.9; 37–84)60.6 (14.7; 38–88)65.1 (11.3; 42–84)55.8 (16.0; 42–84)0.003
     Spinopelvic alignment (PI–LL)–2.9 (8.1; –29–9)4.3 (4.6; –9–10)19.8 (8.2; 10–42)15.9 (4.2; 12–23)<0.001
    Change from baseline
     Lumbar lordosis3.3 (6.3; –10–22)11.2 (7.4; 2–32)0.5 (7.1; –21–21)–10.4 (7.8; –25 to –2)<0.001
     Pelvic incidence1.4 (2.9; –5–11)–0.8 (3.4; –10–4)0.4 (3.8; –5–11)2.5 (3.6; –1–10)0.017
     Spinopelvic alignment (PI–LL)–1.9 (6.5; –21–11)–12.0 (6.9; –30 to –2)–0.2 (7.0; –13–21)13.0 (8.2; 5–29)<0.001
    • Abbreviations: LL, indicates lumbar lordosis; PI, pelvic incidence; PI–LL, pelvic incidence minus lumbar lordosis.

    • ↵a One-way analysis of variance tests were used to categorize differences for each alignment measure between all 4 alignment groups.

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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Mismatch Between Pelvic Incidence and Lumbar Lordosis After Personalized Interbody Fusion: The Importance of Preoperative Planning and Alignment in Degenerative Spine Diseases
Jahangir Asghar, Ashvin I. Patel, Joseph A. Osorio, Justin S. Smith, John Small, Jeffrey P. Mullin, Atman Desai, Michele Temple-Wong, Rodrigo J. Nicolau
International Journal of Spine Surgery Aug 2024, 8638; DOI: 10.14444/8638

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Mismatch Between Pelvic Incidence and Lumbar Lordosis After Personalized Interbody Fusion: The Importance of Preoperative Planning and Alignment in Degenerative Spine Diseases
Jahangir Asghar, Ashvin I. Patel, Joseph A. Osorio, Justin S. Smith, John Small, Jeffrey P. Mullin, Atman Desai, Michele Temple-Wong, Rodrigo J. Nicolau
International Journal of Spine Surgery Aug 2024, 8638; DOI: 10.14444/8638
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Keywords

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  • PI-LL
  • personalized
  • spinopelvic parameters
  • short-segment

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