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Research ArticleLumbar Spine

Segmental Lordosis and Disc Height Discrepancies in Lateral Lumbar Interbody Fusion Using Expandable Cages

Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Masato Sato and Masahiko Watanabe
International Journal of Spine Surgery March 2025, 8726; DOI: https://doi.org/10.14444/8726
Akihiko Hiyama
1 Department of Orthopedic Surgery, Tokai University School of Medicine, Isehara, Japan
MD, PhD
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  • ORCID record for Akihiko Hiyama
  • For correspondence: a.hiyama@tokai.ac.jp
Daisuke Sakai
1 Department of Orthopedic Surgery, Tokai University School of Medicine, Isehara, Japan
MD, PhD
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Hiroyuki Katoh
1 Department of Orthopedic Surgery, Tokai University School of Medicine, Isehara, Japan
MD, PhD
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Masato Sato
1 Department of Orthopedic Surgery, Tokai University School of Medicine, Isehara, Japan
MD, PhD
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Masahiko Watanabe
1 Department of Orthopedic Surgery, Tokai University School of Medicine, Isehara, Japan
MD, PhD
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  • Figure 1
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    Figure 1

    Measurement of radiographic parameters. (A) Preoperative sagittal computed tomography (CT). (B and C) Postoperative sagittal CT. (a) Segmental lordosis. (b) Anterior disc height. (c) Posterior disc height. (d) Foraminal area was measured on CT images.

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    Figure 2

    Measurement of magnetic resonance imaging (MRI) findings. (A) Postoperative sagittal MRI. (B) Postoperative axial MRI. (a) Canal diameter and (b) central canal area were measured as the enclosed area of the spinal canal on sagittal and axial MRI.

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    Figure 3

    Bar graph showing the feature importance scores derived from the random forest regression model used in the sensitivity analysis. The graph illustrates the relative impact of 6 key parameters. Pre-PDH demonstrated the highest importance, indicating its significant influence on postoperative SL outcomes. Abbreviations: ADH, anterior disc height; AvDH, average disc height; PDH, posterior disc height; SL, segmental lordosis;.

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    Figure 4

    Correlation matrix of parameters. The heatmap illustrates the correlation coefficients between key pre- and postoperative parameters. SL, ADH, PDH, AvDH, and cage position are evaluated for their linear relationships. Positive correlations are shown in shades of blue, while negative correlations are depicted in shades of red. The color’s intensity indicates the correlation’s strength, with darker shades representing stronger relationships. Abbreviations: ADH, anterior disc height; AvDH, average disc height; PDH, posterior disc height; SL, segmental lordosis;.

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    Figure 5

    A 55-year-old woman underwent LLIF with PPS for L4 spondylolisthesis. Sagittal CT images before (A) and after surgery (B) are shown. Sagittal MRIs before surgery are shown in (C), and after surgery in (E), while axial MRIs before surgery are shown in (D), and after surgery in (F). Preoperative ADH, PDH, AvDH, and SL were 8.7, 5.8, 7.3, and 6.9 mm, respectively. The predicted values for ADH, PDH, AvDH, and SL were 11.0, 7.9, 9.5, and 9.8 mm, respectively. Postoperative CT showed actual ADH, PDH, AvDH, and SL measurements of 12.8, 9.5, 11.2, and 7.2 mm, respectively. While the DH was greater than predicted, the SL was smaller than expected. MRI revealed significant improvement in dural sac compression. Abbreviations: ADH, anterior disc height; AvDH, average disc height; CT, computed tomography; LLIF, lateral lumbar interbody fusion; MRI, magnetic resonance imaging; PDH, posterior disc height; PPS, percutaneous pedicle screw; SL, segmental lordosis.

Tables

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    Table 1

    RISE-L adjustable lordosis expansion.

    Outcome MeasureNo. of Driver Revolutions
    01234567891011121314
    ADH, mm77.588.599.51010.51111.51212.51313.514
    PDH, mm66.256.56.756.97.157.47.657.98.18.38.558.89.059.3
    SL (°)33.854.75.556.47.258.18.959.810.6511.512.3513.214.115
    • Abbreviations: ADH, anterior disc height; PDH, posterior disc height; SL, segmental lordosis.

    • Note: This table shows the change in anterior-posterior disc height and segmental lordosis angle according to the number of drive screw turns.

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    Table 2

    Characteristics of the subjects in the present study (N = 51).(Table 2)

    CharacteristicValue
    Age, y70.6 (11.7)
    Sex, men/women, n28/23
    Height, cm, mean (SD)159.8 (9.1)
    Body weight, kg, mean (SD)63.9 (13.3)
    BMI, mean (SD)24.8 (3.7)
    Tobacco use, n (%)7 (16)
    Steroid use, n (%)5 (12)
    Indications, n (%)
     LCS+ (LDS)44 (86)
     Degenerative lumbar scoliosis4 (8)
     Lumbar disc herniation2 (4)
     Foraminal stenosis1 (2)
    Levels treated, n (%)
     L1–L20 (0)
     L2–L38 (10)
     L3–L434 (43)
     L4–L537 (47)
     Overall79
    Number of levels fused, n (%)
     1 level26 (51)
     2 levels22 (43)
     3 levels3 (6)
     Mean (SD)1.5 (0.6)
    Operation time, min, mean (SD)128.1 (25.6)
    EBL, mL, mean (SD)92.7 (58.8)
    LOS, d, mean (SD)15.5 (4.1)
    Cage height, mm, mean (SD)10.3 (1.2)
    Cage width, mm, mean (SD)18 (0)
    Cage length, mm, mean (SD)50.8 (4.2)
    Cage position, %, n (%)51.4 (11.0)
    Cage placement, n (%)
     Anterior (<45%)21 (27)
     Central (>45, <55%)23 (29)
     Posterior (>55%)35 (44)
    Cage subsidence, n (%)4 (8)
     Early cage subsidence0 (0)
     Delayed cage subsidence4 (8)
    Transient motor weakness, n (%)4 (8)
    Thigh pain and/or numbness, n (%)6 (12)
    Revision surgery, n (%)4 (8)
    • Abbreviations: BMI, body mass index; EBL, estimated blood loss; LCS, lumbar canal stenosis; LDS, lumbar degenerative spondylolisthesis; LOS, length of stay.

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    Table 3

    Preoperative, postoperative, and change from pre- to postoperative sagittal measurements.

    Outcome MeasurePreoperativePostoperativeΔPost-Pre P a
    SL (°)3.5 (4.2)4.8 (2.8)1.3 (3.6)0.002b
    ADH, mm5.9 (3.3)10.7 (1.8)4.9 (2.7)<0.001b
    PDH, mm3.4 (2.6)7.7 (1.8)4.4 (1.8)<0.001b
    AvDH, mm4.6 (2.7)9.2 (1.5)4.6 (2.0)<0.001b
    FA, mm2 98.4 (37.1)131.2 (39.9)32.7 (29.9)<0.001b
    • Abbreviations: ADH, anterior disc height; ASD, adjacent segment degeneration; AvDH, average disc height; FA, foraminal area; PDH, posterior disc height; SL, segmental lordosis.

    • Note: Data presented as mean (SD).

    • ↵a Comparison with preoperative.

    • ↵b Statistically significant.

    • View popup
    Table 4

    Postoperative vs ideal postoperative.

    Outcome MeasureActual PostoperativePredicted PostoperativeΔPredicted Postoperative-Actual Postoperative P a
    SL (°)4.8 (2.8)8.7 (2.0)3.9 (3.5)<0.001b
    ADH, mm10.7 (1.8)10.4 (1.2)−0.4 (1.5)0.287
    PDH, mm7.7 (1.8)7.6 (0.5)−0.2 (1.6)0.721
    AvDH, mm9.2 (1.5)9.0 (0.9)−0.3 (1.2)0.494
    • Abbreviations: ADH, anterior disc height; AvDH, average disc height; PDH, posterior disc height; SL, segmental lordosis.

    • Note: Data reported as mean (SD).

    • ↵a Comparison with actual and ideal postoperative.

    • ↵b Statistically significant.

    • View popup
    Table 5

    Radiographic evaluation of canal dimension changes (canal diameter and central canal area) in patients pre- and postoperatively using MRI.

    Outcome MeasurePreoperativeImmediate PostoperativeΔChanges P a
    CD, mm5.0 (2.4)8.3 (2.5)3.3 (2.0)<0.001b
    CCA, mm2 55.8 (35.8)89.7 (36.1)33.9 (22.9)<0.001b
    • Abbreviations: CCA, central canal area; CD, canal diameter.

    • Note: Data presented as mean (SD).

    • ↵a Comparison with preoperative.

    • ↵b Statistically significant.

    • View popup
    Table 6

    Correlation between DH and SL with changes in CD and CCA.

    VariablePre-ADHPre-PDHPre-AvDHPre-SL
    ΔCD
     r −0.091−0.078−0.1080.082
     P 0.4320.5010.3490.478
    ΔCCA
     r −0.118−0.106−0.1340.033
     P 0.3060.3570.2440.777
    VariablePost-ADHPost-PDHPost-AvDHPost-SL
    ΔCD
     r −0.0760.080−0.012−0.117
     P 0.5120.4870.9150.311
    ΔCCA
     r 0.0170.1260.0660.005
     P 0.8840.2750.5690.966
    VariableΔADHΔPDHΔAvDHΔSL
    ΔCD
     r 0.0130.1950.095−0.122
     P 0.9090.0890.4110.291
    ΔCCA
     r 0.1200.272a 0.199−0.010
     P 0.2980.0170.0830.928
    • Abbreviations: ADH, anterior disc height; AvDH, average disc height; PDH, posterior disc height; SL, segmental lordosis; ΔCCA, change of central canal area; ΔCD, change of canal diameter.

    • ↵a Statistically significant.

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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Segmental Lordosis and Disc Height Discrepancies in Lateral Lumbar Interbody Fusion Using Expandable Cages
Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Masato Sato, Masahiko Watanabe
International Journal of Spine Surgery Mar 2025, 8726; DOI: 10.14444/8726

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Segmental Lordosis and Disc Height Discrepancies in Lateral Lumbar Interbody Fusion Using Expandable Cages
Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Masato Sato, Masahiko Watanabe
International Journal of Spine Surgery Mar 2025, 8726; DOI: 10.14444/8726
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Keywords

  • lateral lumbar interbody fusion
  • expandable cage
  • indirect decompression
  • segmental lordosis
  • disc height

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