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Research ArticleOther and Special Categories

Adult Spinal Deformity Over 70 Years of Age: A 2-Year Follow-Up Study

Cem Karabulut, Selim Ayhan, Selcen Yuksel, Vugar Nabiyev, Alba Vila-Casademunt, Ferran Pellise, Ahmet Alanay, Francisco Javier Sanchez Perez-Grueso, Frank Kleinstuck, Ibrahim Obeid, Emre Acaroglu and European Spine Study Group
International Journal of Spine Surgery August 2019, 6046; DOI: https://doi.org/10.14444/6046
Cem Karabulut
1ARTES Spine Center, Ankara, Turkey
MD
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Selim Ayhan
1ARTES Spine Center, Ankara, Turkey
2Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey
MD
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Selcen Yuksel
3Yildirim Beyazit University, Department of Biostatistics, Ankara, Turkey
PHD
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Vugar Nabiyev
1ARTES Spine Center, Ankara, Turkey
MD
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Alba Vila-Casademunt
4Hospital Universitari Vall d'Hebron, Barcelona, Spain
PHD
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Ferran Pellise
4Hospital Universitari Vall d'Hebron, Barcelona, Spain
MD, PHD
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Ahmet Alanay
5Acibadem Mehmet Ali Aydinlar University, Department of Orthopaedics and Traumatology, Istanbul, Turkey
MD
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Francisco Javier Sanchez Perez-Grueso
6Hospital Universitari La Paz, Madrid, Spain
MD
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Frank Kleinstuck
7Schulthess Klinik, Zürich, Switzerland
MD
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Ibrahim Obeid
8Bordeaux University Hospital, Bordeaux, France
MD
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Emre Acaroglu
9Ankara Spine Center, Ankara, Turkey
MD
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4Hospital Universitari Vall d'Hebron, Barcelona, Spain
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ABSTRACT

Background Treatment of adult spinal deformity (ASD) in elderly patients remains controversial. The aim of this study was to identify the factors leading to the surgical treatment by comparing the baseline characteristics of operative versus nonoperative patients, to evaluate the safety and efficacy of surgery, and to compare operative and nonoperative management of elderly ASD patients at the end of the 2-year follow-up period.

Methods Retrospective review of a multicenter, prospective ASD database was performed. Patients over 70 years of age with ASD who were scheduled to undergo surgical treatment and who were treated and/or followed without surgical intervention participated in the study. Demographic, clinical, surgical, and radiological characteristics and health-related quality-of-life (HRQOL) (Core Outcome Measures Index [COMI], Oswestry Disability Index [ODI], Short-Form-36 Mental Component Summary [SF-36 MCS], Short-Form-36 Physical Component Summary [SF36-PCS], and Scoliosis Research Society-22 [SRS-22]) parameters of such group of patients were evaluated pre- and posttreatment.

Results A total 90 patients (females: 71, males: 29; operative: 61, nonoperative: 29) made up the study group. The comparison between the operative and the nonoperative groups at baseline showed statistical significance for all the HRQOL parameters and the major coronal Cobb angle (P < .05). The calculated optimal cutoff values to diverge operative and nonoperative groups for COMI, ODI, SF-36 PCS, and SRS-22 were 5.7, 37.0, 37.5, and 3.2, respectively (P < .05). All operative patients were treated with posterior surgery. Overall, 135 complications (71 major, 64 minor) and 1 death were observed. Surgically treated patients were found to be improved both clinically and in HRQOL parameters 2 years after surgery for all HRQOL parameters except SF-36 MCS, even in the presence of complications (P < .05), while nonoperative patients have not changed or deteriorated at the end of 2 years.

Conclusions Despite a relatively high incidence of complications, the likelihood of achieving a clinically significant and relevant HRQOL improvement was superior for patients who were treated surgically in the present population.

  • adult spinal deformity
  • complications
  • elderly
  • nonoperative
  • outcomes
  • surgery
  • treatment

Footnotes

  • Disclosures and COI: The authors of this article have no competing interests that influence the results and discussion of this article. Cem Karabulut: Grants/research support: Medtronic. Selim Ayhan: None. Selcen Yuksel: None. Vugar Nabiyev: None. Ferran Pellise: Grants/research support: Depuy Synthes, K2M; Consultant: Depuy Synthes. Alba Vila-Casademunt: Grants/research support: Depuy Synthes. Ahmet Alanay: Grants/research support: Depuy Synthes; Consulting: Depuy Synthes, Stryker, Medtronic. Francisco JS Perez-Grueso: Grants/research support: Depuy Synthes; Consulting: Depuy Synthes Spine. Frank Kleinstuck: Grants/research support: Depuy Synthes. Ibrahim Obeid: Grants/research support: Depuy Synthes; Consulting: Depuy Synthes, Medtronic, Alphatec. Emre Acaroglu: Grants/research Support: DePuy Synthes, Medtronic, Stryker Spine; Speaker's Bureau: AO Spine, Medtronic, Stryker Spine, Zimmer Biomet; Advisory Board or Panel: AO Spine; Stock/Shareholder: IncredX (self-managed).

  • ©International Society for the Advancement of Spine Surgery
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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Adult Spinal Deformity Over 70 Years of Age: A 2-Year Follow-Up Study
Cem Karabulut, Selim Ayhan, Selcen Yuksel, Vugar Nabiyev, Alba Vila-Casademunt, Ferran Pellise, Ahmet Alanay, Francisco Javier Sanchez Perez-Grueso, Frank Kleinstuck, Ibrahim Obeid, Emre Acaroglu, European Spine Study Group
International Journal of Spine Surgery Aug 2019, 6046; DOI: 10.14444/6046

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Adult Spinal Deformity Over 70 Years of Age: A 2-Year Follow-Up Study
Cem Karabulut, Selim Ayhan, Selcen Yuksel, Vugar Nabiyev, Alba Vila-Casademunt, Ferran Pellise, Ahmet Alanay, Francisco Javier Sanchez Perez-Grueso, Frank Kleinstuck, Ibrahim Obeid, Emre Acaroglu, European Spine Study Group
International Journal of Spine Surgery Aug 2019, 6046; DOI: 10.14444/6046
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Keywords

  • adult spinal deformity
  • complications
  • elderly
  • nonoperative
  • outcomes
  • surgery
  • treatment

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