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Research ArticleArticles

Bone substitutes and expanders in Spine Surgery: A review of their fusion efficacies

Abhijeet Kadam, Paul W Millhouse, Christopher K Kepler, Kris E. Radcliff, Michael G. Fehlings, Michael E. Janssen, Rick C. Sasso, James J. Benedict and Alexander R Vaccaro
International Journal of Spine Surgery January 2016, 10 33; DOI: https://doi.org/10.14444/3033
Abhijeet Kadam
1Pennsylvania Hospital of the University of Pennsylvania Health System, Philadelphia, PA
MD
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Paul W Millhouse
2Rothman Institute, Philadelphia, PA
MD
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Christopher K Kepler
2Rothman Institute, Philadelphia, PA
MD, MBA
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Kris E. Radcliff
2Rothman Institute, Philadelphia, PA
MD
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Michael G. Fehlings
3Toronto Western Hospital, Toronto, Canada
MD, PhD, FRCSC
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Michael E. Janssen
4Center for Spine & Orthopaedics, Denver, CO
DO
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Rick C. Sasso
5Indiana Spine Group, Indianapolis, IN
MD
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James J. Benedict
6Cerapedics, Westminster, CO
PhD, MD
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Alexander R Vaccaro
2Rothman Institute, Philadelphia, PA
MD, PhD, MBA
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Article Information

vol. 10 33
DOI 
https://doi.org/10.14444/3033

Published By 
International Journal of Spine Surgery
Online ISSN 
2211-4599
History 
  • Published online January 1, 2016.

Copyright & Usage 
Copyright © 2016 ISASS - This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery

Author Information

  1. Abhijeet Kadam, MD1,
  2. Paul W Millhouse, MD2,
  3. Christopher K Kepler, MD, MBA2,
  4. Kris E. Radcliff, MD2,
  5. Michael G. Fehlings, MD, PhD, FRCSC3,
  6. Michael E. Janssen, DO4,
  7. Rick C. Sasso, MD5,
  8. James J. Benedict, PhD, MD6 and
  9. Alexander R Vaccaro, MD, PhD, MBA2
  1. 1Pennsylvania Hospital of the University of Pennsylvania Health System, Philadelphia, PA
  2. 2Rothman Institute, Philadelphia, PA
  3. 3Toronto Western Hospital, Toronto, Canada
  4. 4Center for Spine & Orthopaedics, Denver, CO
  5. 5Indiana Spine Group, Indianapolis, IN
  6. 6Cerapedics, Westminster, CO
  1. Corresponding Author
    Abhijeet Kadam, MD, Pennsylvania Hospital of the University of Pennsylvania Health System, Philadelphia, PA 19107. abhijeetsr71{at}gmail.com.
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International Journal of Spine Surgery
Vol. 10
1 Jan 2016
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Bone substitutes and expanders in Spine Surgery: A review of their fusion efficacies
Abhijeet Kadam, Paul W Millhouse, Christopher K Kepler, Kris E. Radcliff, Michael G. Fehlings, Michael E. Janssen, Rick C. Sasso, James J. Benedict, Alexander R Vaccaro
International Journal of Spine Surgery Jan 2016, 10 33; DOI: 10.14444/3033

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Bone substitutes and expanders in Spine Surgery: A review of their fusion efficacies
Abhijeet Kadam, Paul W Millhouse, Christopher K Kepler, Kris E. Radcliff, Michael G. Fehlings, Michael E. Janssen, Rick C. Sasso, James J. Benedict, Alexander R Vaccaro
International Journal of Spine Surgery Jan 2016, 10 33; DOI: 10.14444/3033
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Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Allografts
    • Demineralized bone matrix (DBM)
    • Ceramics
    • Bone morphogenic proteins (BMPs)
    • Autologous growth factors (AGF)
    • Allograft cellular bone matrix (ACBM) / Stem cell based products
    • Synthetic Peptides
    • Discussion and conclusions
    • Disclosures & COI
    • Acknowledgements
    • References
  • Info & Metrics
  • PDF

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  • Allografts and Spinal Fusion
  • Demineralized Bone Matrix in Spine Surgery: A Review of Current Applications and Future Trends
  • Comparative Efficacy of Commonly Available Human Bone Graft Substitutes as Tested for Posterolateral Fusion in an Athymic Rat Model
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  • Revision of Minimally Invasive Sacroiliac Joint Fixation: Technical Considerations and Case Studies Using Decortication and Threaded Implant Fixation
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Keywords

  • bone substitutes
  • allografts
  • demineralized bone matrix (DBM)
  • spine fusion
  • ceramics
  • β tricalcium phosphate (β-tcp)
  • hydroxyapatite
  • rhBMP-2
  • osteogenic protein-1 (op-1)
  • autologous growth factors
  • i-factor
  • synthetic peptides

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