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Research ArticleArticles

Sciatica caused by disc herniation: Why is Chymopapain Chemonucleolysis denied to our patients?

Douglas Wardlaw
International Journal of Spine Surgery January 2016, 10 44; DOI: https://doi.org/10.14444/3044
Douglas Wardlaw
Formerly Consultant Spinal Surgeon, Department of Orthopaedics, NHS Grampian, Woodend Hospital, Aberdeen, Scotland, UK, Honorary Professor, The Robert Gordon University, Aberdeen, Scotland, UK
MB ChB ChM FRCSEd
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Article Figures & Data

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    Table 1

    Macnab Criteria (Macnab I. “negative disc exploration: an analysis of the cause of nerve root involvement in sixtyeight patients.” J Bone Joint Surg (Am) 1971 ;53:891-903).

    • Excellent: No pain; no restriction of activity.

    • Good: Occasional back or leg pain of sufficient severity to interfere with the patient’s ability to do his normal work or his capacity to enjoy himself in his leisure hours.

    • Fair: Improved functional capacity, but handicapped by intermittent pain of sufficient severity to curtail or modify work or leisure activities.

    • Poor: No improvement or insufficient improvement to enable increase in activities; further operative intervention required.

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    Table 2

    Indications.

    IndicationN (%)
    Classical515 (85%)
    Non-Classical90 (15%)
    Leg pain with significant back pain34 (6%)
    Far lateral/foraminal herniation14 (2%)
    Recurrent disc herniation following surgery3 (0.5%)
    dominant neurology with minimal leg pain3 (0.5%)
    two level herniations27 (4%)
    Cauda equina syndrome1 (0.1%)
    • View popup
    Table 3

    Patient Demographics (605 cases, 1991-2000).

    Mean Age47 years (range 17-88)
    SexM 56% W 44%
    Duration of Symptoms10 months (range 1 - 120)
    Radicular painRight (51%); left (49%)
    InvestigationMyelogram 42 patients; CT Scan 206 patients; MRI 357 patients
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    Table 4

    Distribution of injections.

    L5-S1296
    L4-5263
    L3-416
    L2-33
    L4-5 & L5-S125
    L3-4 & L4-52
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    Table 5

    Results.

    Average Follow-up62 months (range 12 - 123)
    Macnab (Excellent and Good)76%
    Satisfaction78%
    Surgical Intervention14%
    Fusion/Stabilisation4% (24 patients)
    Decompression9% (54 patients)
    Chemonucleolysis1% (6 patients)
    • SF-36 scores generally correlated with age/sex of normal scores for the local population.

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    Table 6

    Complications.

    Infection0
    Neurological0
    Anaphylaxis0
    Recurrent herniation0
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International Journal of Spine Surgery
Vol. 10
1 Jan 2016
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Sciatica caused by disc herniation: Why is Chymopapain Chemonucleolysis denied to our patients?
Douglas Wardlaw
International Journal of Spine Surgery Jan 2016, 10 44; DOI: 10.14444/3044

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Sciatica caused by disc herniation: Why is Chymopapain Chemonucleolysis denied to our patients?
Douglas Wardlaw
International Journal of Spine Surgery Jan 2016, 10 44; DOI: 10.14444/3044
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Keywords

  • Chymopapain
  • chemonucleolysis
  • sciatica
  • disc herniaion
  • lumbar spine
  • back pain
  • complications
  • long term follow up
  • outcome

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