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Research ArticleArticles

Clinical Experiences of Non-fusion Dynamic Stabilization Surgery for Adjacent Segmental Pathology after Lumbar Fusion

Soo Eon Lee, Tae-Ahn Jahng and Hyun-Jib Kim
International Journal of Spine Surgery January 2016, 10 8; DOI: https://doi.org/10.14444/3008
Soo Eon Lee
1Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea
MD
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Tae-Ahn Jahng
2Seoul National University Bundang Hospital, Seoul, Korea
3Seoul National University College of Medicine, Seoul, Korea
MD, PhD
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Hyun-Jib Kim
2Seoul National University Bundang Hospital, Seoul, Korea
MD, PhD
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  • Fig. 1
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    Fig. 1

    The application of Dynesys system (case No. 9). A 70-year-old female patient was diagnosed with spinal stenosis and spondylolisthesis (A) and underwent fusion surgery at L4-5 previously 8 years prior to her visit (B). She developed back pain with intermittent claudication recently in the past year. Spinal stenosis was revealed at L3-4, and dynamic stabilization surgery was performed with Dynesys system at L3-4 (C). Postoperatively 3 years later, her symptoms were much improved with stable radiographic findings (D).

  • Fig. 2
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    Fig. 2

    The application of NFlex system (case No. 14). A 46-year-old female patient underwent fusion surgery at L3-4 previously 2 years prior to her visit (A), but she complained of persistent pain (B). With more progressed spinal stenosis at L4-5, she underwent dynamic stabilization surgery with the NFlex system (C). No significant radiologic findings at adjacent segments were observed (D), but she maintained medical treatment for pain reduction.

  • Fig. 3
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    Fig. 3

    Clinical outcomes. A) VAS change. Before non-fusion surgery, VAS was 7.4, and it gradually decreased after non-fusion surgery. VAS was 4.2 at 36 months postoperatively (p= 0.027). B) ODI change. ODI showed a change from 58.5% to 35.0% 36 months postoperatively (p=0.018).

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    Fig. 4

    MRI changes. A) Disc degeneration. Each segmental lumbar intervertebral disc gradually degenerated from the time before fusion surgery to after non-fusion surgery. Before non-fusion surgery, disc degeneration at L3-4 (*) showed statistically significant changes compared to that before fusion surgery (p=0.046). Between non-fusion surgery and the last MRI evaluation, the change at L1-2 (**) was statistically significant (p=0.032). B) Central stenosis. In the state between fusion and non-fusion surgery, stenosis at L3-4 (*) demonstrated significant degeneration (p=0.041) despite the fact that the L4-5 segment was decompressed by the fusion surgery. After non-fusion surgery, L3-4 (**) sufficient decompression was accomplished (p=0.041), but other instances of segmental stenosis did not show statistically significant changes. C) Facet joint degeneration. Each segmental facet joint was degenerated as time passed. However, the changes between fusion and non-fusion surgery and between non-fusion surgery and the last follow-up did not show statistical significance.

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    Fig. 5

    The change of disc degeneration on MRI (case No. 12). A 69-year-old female patient had spinal stenosis at L4-5 with multilevel disc degeneration (A). After a previous fusion surgery at L4-5 two years prior to her visit, spinal stenosis by thickening of the ligamentum flavum and disc degeneration at L2-3-4 had progressed (B). She underwent decompression and dynamic stabilization surgery at L2-3-4. At the postoperative 12-month MRI, segments at L1-2 and L5-S1 showed progression of disc degeneration (C).

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    Fig. 6

    Disc degeneration on lateral radiographs. Upon a comparison of disc degeneration before fusion and before non-fusion surgery and between each postoperative follow-up period, disc degeneration at L3-4 (*) was noted when comparing the state before the fusion surgery and that before the non-fusion surgery. After non-fusion dynamic stabilization surgery, disc degeneration gradually progressed, especially at L1-2 and L2-3.

Tables

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    Table 1

    MRI evaluation for disc degeneration, central stenosis, and facet joint degeneration.

    Classification of disc degeneration
    GradeSignal intensityStructureDistinction of nucleus and anulus
    IHyperintense, isointense to CSFHomogeneous, bright whiteClear
    IIHyperintense, isointense to CSFInhomogeneous with or without horizontal bandsClear
    IIIIntermediateInhomogenous, grayUnclear
    IVIntermediate to hypointenseInhomogenous, gray to blackLost
    VHypointenseInhomogenous, blackLost
    Classification of central canal stenosis
    GradeDefinition
    0No lumbar stenosis without obliteration of anterior CSF space
    1Mild stenosis with separation of all cauda equina
    2Moderate stenosis with some cauda equine aggregated
    3Severe stenosis with none of the cauda equine separated
    Classification of facet joint degeneration
    GradeCriteria
    0Normal facet joint space (2-4mm width)
    1Narrowing of the facet joint space (< 2mm) and/or small osteophyte and/or mild hypertrophy of the articular process
    2Narrowing of the facet joint space and/or moderate osteophyte and/or moderate hypertrophy of the articular process and/or mild subarticular bone erosions
    3Narrowing of the facet joint space and/or large osteophytes and/or severe hypertrophy of the articular process and/or severe subarticular bone erosions and/or subchondral cysts
    • CSF: cerebrospinal fluid.

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    Table 2

    Grading of disc degeneration on plain radiograph

    GradeDisc space narrowingOsteophyteEndplate sclerosis
    I---
    II+--
    III±+-
    IV±±+
    • ‘+’ indicates present; ‘-’, absence; ‘±’, either present or absent.

    • View popup
    Table 3

    Patient characteristics.

    No.GenderAge at fusion surgery (yrs)Age at non-fusion surgery (yrs)Previous fusion segmentPain free period after fusion (m)Interval between fusion and non-fusion surgery (m)Feature of ASPRecent non-fusion segmentPedicle-based dynamic stabilization systemClinical ASP after non-fusion surgeryRadiologic ASP after non-fusion surgery
    1M4959L3-472120Stenosis at L4-5 DDD at L2-3, L4-5L4-5Dynesys++
    2F6067L4-5-S1Persistent pain84Stenosis & DDD at L3-4L3-4DynesysPersistent pain+
    3F5661L4-5-S1Persistent pain60Stenosis & DDD at L3-4L3-4DynesysPersistent pain+
    4M6368L4-5-S11256Stenosis at L3-4L3-4Dynesys--
    5F4960L4-596120Stenosis, DDD & SPL at L2-3-4L2-3-4-5DynesysPersistent pain-
    6F5661L3-4-53660Stenosis at L2-3L2-3Dynesys--
    7F6163L4-5Persistent pain26Stenosis at L3-4-5 SPL at L4-5L3-4-5Dynesys++
    8F4859L4-548120Stenosis & DDD at L3-4L3-4Dynesys--
    9F6270L4-58294Stenosis & DDD at L3-4L3-4Dynesys--
    10F5157L4-5-S12070Stenosis & DDD at L3-4L3-4Dynesys--
    11F5865L4-5-S13682Stenosis at L1-2-3L1-2-3Dynesys--
    12F6769L4-52022Stenosis & DDD at L2-3-4L2-3-4NFlex-+
    13F6470L4-5-S11260Stenosis at L3-4L3-4NFlex+-
    14F4346L3-4Persistent pain25Stenosis & DDD at L4-5L4-5NFlex+-
    15F5657L2-3Persistent pain6Stenosis at L4-5L4-5NFlex--
    • DDD: degenerative disc disease; SPL: spondylolisthesis; ‘+’: developed, ‘-’: absent.

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International Journal of Spine Surgery
Vol. 10
1 Jan 2016
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Clinical Experiences of Non-fusion Dynamic Stabilization Surgery for Adjacent Segmental Pathology after Lumbar Fusion
Soo Eon Lee, Tae-Ahn Jahng, Hyun-Jib Kim
International Journal of Spine Surgery Jan 2016, 10 8; DOI: 10.14444/3008

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Clinical Experiences of Non-fusion Dynamic Stabilization Surgery for Adjacent Segmental Pathology after Lumbar Fusion
Soo Eon Lee, Tae-Ahn Jahng, Hyun-Jib Kim
International Journal of Spine Surgery Jan 2016, 10 8; DOI: 10.14444/3008
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Keywords

  • lumbar spine
  • non-fusion
  • Dynamic stabilization system
  • dynesys
  • NFlex
  • adjacent segment pathology

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