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Research ArticleBiomechanics

Differences in Trabecular Bone, Cortical Shell, and Endplate Microstructure Across the Lumbar Spine

VIVEK PALEPU, SAI DEEPA RAYAPROLU and SRINIDHI NAGARAJA
International Journal of Spine Surgery August 2019, 13 (4) 361-370; DOI: https://doi.org/10.14444/6049
VIVEK PALEPU
US Food and Drug Administration, Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Division of Applied Mechanics, Silver Spring, Maryland
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SAI DEEPA RAYAPROLU
US Food and Drug Administration, Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Division of Applied Mechanics, Silver Spring, Maryland
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SRINIDHI NAGARAJA
US Food and Drug Administration, Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Division of Applied Mechanics, Silver Spring, Maryland
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    Figure 1

    Endplate thickness measurements at 5 different points on endplate from the mid-coronal slice of vertebra.

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    Figure 2

    Axial view of (a) 3-dimensional endplate structure, (b) axial reference plane created based on 3 points on apophyseal ring, and sagittal view of (c) axial reference plane on the endplate highlighting the endplate concavity space (shaded region) and (d) endplate concavity space with location of maximum concavity depth (highlighted with red dot).

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    Figure 3

    Vertebral cortex thickness measurements at 9 different locations at the mid-axial slice of vertebra.

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    Figure 4

    Mean and standard deviations of (a) trabecular bone volume fraction, (b) trabecular thickness, (c) trabecular number, and (d) volumetric bone mineral density for all lumbar vertebrae (*P ≤ .05; †P ≤ .1).

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    Figure 5

    Mean and standard deviations of (a) average endplate thickness and (b) maximum endplate concavity depth in millimeters for superior and inferior endplates of all lumbar vertebrae. Student paired t test analyses were performed to obtain statistical significance between superior and inferior endplates (*P ≤ .05).

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    Figure 6

    Mean and standard deviations of vertebral cortical thickness for (a) posterior, (b) anterior, (c) left, and (d) right cortex regions for all lumbar vertebrae (*P ≤ .05; †P < .1).

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    Figure 7

    Mean and standard deviations of vertebral cortical thickness for (a) L1, (b) L2, (c) L3, (d) L4, and (e) L5 vertebrae depicting differences in thickness values between posterior, anterior, left, and right cortex regions of vertebral body (*P ≤ .05; †P < .1).

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International Journal of Spine Surgery
Vol. 13, Issue 4
1 Aug 2019
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Differences in Trabecular Bone, Cortical Shell, and Endplate Microstructure Across the Lumbar Spine
VIVEK PALEPU, SAI DEEPA RAYAPROLU, SRINIDHI NAGARAJA
International Journal of Spine Surgery Aug 2019, 13 (4) 361-370; DOI: 10.14444/6049

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Differences in Trabecular Bone, Cortical Shell, and Endplate Microstructure Across the Lumbar Spine
VIVEK PALEPU, SAI DEEPA RAYAPROLU, SRINIDHI NAGARAJA
International Journal of Spine Surgery Aug 2019, 13 (4) 361-370; DOI: 10.14444/6049
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Keywords

  • endplate concavity depth
  • trabecular bone microstructure
  • vertebral cortex thickness
  • endplate thickness
  • lumbar spine
  • anatomy

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