Article Figures & Data
Figures
- Figure 1
Preoperative T2 magnetic resonance imaging (MRI) complete spine images showing extensive metastatic disease of the spine. (Left) Sagittal T2 MRI of the upper spine showing pathologic compression fracture of the T9 vertebral body with retropulsion of the posterior vertebral body obliterating the cerebrospinal fluid space. (Middle) Sagittal T2 MRI of the lower spine showing extensive metastatic disease throughout the lumbar spine. (Right) Axial T2 MRI at the level of the T9 vertebral body.
- Figure 2
Histologic and immunohistochemical sections of metastatic paraganglioma biopsy specimen. (A) Hematoxylin-eosin stain of metastatic paraganglioma (×60). Histologic sections of the biopsy specimen showing an epithelioid proliferation of cells with nested architecture (“Zellballen”) with a delicate tumor vascular network between nests. The epithelioid cells show round to ovoid nuclei, minimal nuclear pleomorphism, and stippled chromatin with abundant granular amphophilic cytoplasm. Mitotic figures are seen at 7 in 10 high-power fields. (B) Immunohistochemical stain for synaptophysin showing positive granular cytoplasmic staining in tumor cells (×20). (C) Immunohistochemical stain for S-100 highlighting fragmented network of sustenacular cells surrounding tumor cells (×20). (D) Immunohistochemical stain for succinate dehydrogenase subunit B (SDHB) showing absence of SDHB among tumor cells, while maintaining positive internal control within vascular endothelium (×20).
- Figure 3
Postoperative sagittal x-ray of the spine showing instrumentation.
- Figure 4
Post-operative T2 magnetic resonance imaging of thoracic spine at 1.5 years showing stable disease.
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