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Research ArticleMinimally Invasive Surgery

Opioid Prescription Monitoring in Preoperative and Postoperative Sacroiliac Joint Fusion Patients

Nolan M. Wessell, Emily Wolverton, Phillip Ross, Michelle Akiyama, Emily Lindley and Vikas Patel
International Journal of Spine Surgery June 2022, 16 (3) 498-504; DOI: https://doi.org/10.14444/8240
Nolan M. Wessell
1 Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO, USA
MD
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Emily Wolverton
2 University of Colorado School of Medicine, Aurora, CO, USA
BS
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Phillip Ross
3 Department of Orthopedic Surgery, University of Rochester, NY, USA
MD
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Michelle Akiyama
4 Medicrea, New York, NY, USA
MS
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Emily Lindley
1 Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO, USA
PhD
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Vikas Patel
1 Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO, USA
MD
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    Figure

    Average opioid prescriptions before and after sacroiliac joint fusion. Mean morphine milligram equivalents per day (MME/d) as reported per the Colorado Prescription Drug Monitoring Program data as above in Table 1 with linear regression superimposed. No significant differences in mean MME/d.

Tables

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    Table 1

    Quantity of opioids prescribed over time (N = 45).

    Follow-UpMME/d, mean (SD) P Valuea
    6 mo preoperative45.8 (63.1)0.74
    3 mo preoperative47.2 (57.8)NA
    3 mo postoperative56.8 (64.7)0.29
    6 mo postoperativeb 37.9 (61.6)0.17
    9 mo postoperative47.5 (65.2)0.97
    12 mo postoperative52.0 (58.8)0.61
    • P (T), the 2-sided paired T test.

    • ↵a P value based on 2-sided paired t test (relative to 3 mo before the operation).

    • ↵b The difference in mean opioid consumption between 3- and 6-mo postoperative follow-ups was statistically significant (P = 0.01).

    • MME, morphine milligram equivalents.

    • View popup
    Table 2

    Impact of sex on quantity of opioids prescribed over time (N = 62).

    Follow-UpSexMME/d, mean (SD) P Valuea
    6 mo preoperativeF37.6 (46.9)0.06
    M74.1 (97.9)
    3 mo preoperativeF42.4 (44.1)0.23
    M63.7 (90.7)
    3 mo postoperativeF56.1 (67.0)0.49
    M59.2 (55.1)
    6 mo postoperativeF34.5 (49.9)0.32
    M49.9 (57.2)
    9 mo postoperativeF38.2 (52.7)0.07
    M79.3 (92.1)
    12 mo postoperativeF50.5 (60.4)0.64
    M57.1 (54.7)
    • ↵a P value based on the Wilcoxon nonparametric test.

    • F, female; M, male; MME, morphine milligram equivalents.

    • View popup
    Table 3

    Impact of anxiety/depression on quantity of opioids prescribed over time (N = 62).

    Follow-UpAnxiety/DepressionMME/d, mean (SD) P Valuea
    6 mo preoperativeYes44.8 (54.8)0.85
    No47.9 (69.4)
    3 mo preoperativeYes47.0 (51.9)0.91
    No48.7 (62.5)
    3 mo postoperativeYes57.0 (67.8)0.94
    No58.1 (63.8)
    6 mo postoperativeYes47.3 (50.6)0.09
    No32.6 (52.4)
    9 mo postoperativeYes51.3 (63.3)0.51
    No45.6 (68.0)
    12 mo postoperativeYes46.6 (46.9)0.89
    No55.9 (66.9)
    • ↵a P value based on teh Wilcoxon nonparametric test.

    • MME, morphine milligram equivalents.

    • View popup
    Table 4

    Correlation between age and dose of opioids prescribed over time (N = 62).

    Follow-Up r P Value
    6 mo preoperative0.080.52
    3 mo preoperative0.050.69
    3 mo postoperative0.030.83
    6 mo postoperative0.010.91
    9 mo postoperative0.150.22
    12 mo postoperative0.070.54
    • View popup
    Table 5

    Correlation between body mass index and dose of opioids prescribed over time (N = 62).

    Follow-Up r P Value
    6 mo preoperative0.270.033
    3 mo preoperative0.160.19
    3 mo postoperative0.190.13
    6 mo postoperative0.250.049
    9 mo postoperative0.190.21
    12 mo postoperative0.060.64
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Opioid Prescription Monitoring in Preoperative and Postoperative Sacroiliac Joint Fusion Patients
Nolan M. Wessell, Emily Wolverton, Phillip Ross, Michelle Akiyama, Emily Lindley, Vikas Patel
International Journal of Spine Surgery Jun 2022, 16 (3) 498-504; DOI: 10.14444/8240

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Opioid Prescription Monitoring in Preoperative and Postoperative Sacroiliac Joint Fusion Patients
Nolan M. Wessell, Emily Wolverton, Phillip Ross, Michelle Akiyama, Emily Lindley, Vikas Patel
International Journal of Spine Surgery Jun 2022, 16 (3) 498-504; DOI: 10.14444/8240
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