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Research ArticleLumbar Spine

Increasing Nonconcurrent Overlapping Surgery Is Not Associated With Outcome Changes in Lumbar Fusion

Ali S. Farooqi, Austin J. Borja, Donald K.E.D. Detchou, Gregory Glauser, Krista Strouz, Scott D. McClintock and Neil R. Malhotra
International Journal of Spine Surgery August 2022, 16 (4) 651-659; DOI: https://doi.org/10.14444/8305
Ali S. Farooqi
1 Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA
BA
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Austin J. Borja
1 Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA
BA
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Donald K.E.D. Detchou
1 Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA
BA
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Gregory Glauser
1 Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA
MD, MBA, MA
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Krista Strouz
2 McKenna EpiLog Fellowship in Population Health at the University of Pennsylvania, Philadelphia, USA
3 The West Chester Statistical Institute and Department of Mathematics, West Chester University, West Chester, USA
BS
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Scott D. McClintock
3 The West Chester Statistical Institute and Department of Mathematics, West Chester University, West Chester, USA
PhD
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Neil R. Malhotra
1 Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA
MD
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  • Article
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Article Figures & Data

Figures

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  • Figure 1
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    Figure 1

    Flowchart of lumbar fusion cases included within the present study.

  • Figure 2
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    Figure 2

    Comparison of baseline health characteristics, distribution of comorbidities, and operative time among patients with the most and least amount of surgical overlap. *Significance at P value <0.05. ASA, American Society of Anesthesiologists grade; CCI, Charlson Comorbidity Index score; CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; DM, diabetes mellitus; HIV, human immunodeficiency virus; LD, liver disease; MI, myocardial infarction; PUD, peptic ulcer disease; PVD, peripheral vascular disease; RA, rheumatoid arthritis.

  • Figure 3
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    Figure 3

    Distribution of short-term outcomes following single-level, posterior lumbar fusion. No differences were observed in any morbidity or mortality outcomes between exact matched cohorts. ED, emergency department.

Tables

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    Table 1

    Characteristics of patients whose surgeries had the least amount of overlap (bottom 40% of patients with overlapping surgeries) and the most amount of overlap (top 10% of patients with overlapping surgeries).

    VariableLeast Overlap (N = 520)Most Overlap (N = 131) P Value
    Age (y), mean (range)60.30 (24–88)63.90 (26–87) 0.001
    Gender, n (%)0.96
     Male225 (43.3%)57 (43.5%)
     Female295 (56.7%)74 (56.5%)
    Race, n (%) Asian6 (1.2%)1 (0.8%)0.55
     Black55 (10.6%)12 (9.2%)
     White441 (84.8%)117 (89.3%)
     Hispanic4 (0.8%)0 (0%)
     Unknown10 (1.9%)0 (0%)
     Other2 (0.4%)1 (0.8%)
     East Indian2 (0.4%)0 (0%)
    Insurance, n (%) 0.017
     
     
     
     
     
     Commercial20 (3.8%)2 (1.5%)
     Medicare213 (41.0%)73 (55.7%)
     Medicaid26 (5.0%)4 (3.1%)
     Managed care192 (36.9%)33 (25.2%)
     Blue cross69 (13.3%)19 (14.5%)
    Tobacco use within past 12 mo, n (%)0.08
     Yes81 (15.6%)11 (8.4%)
     No437 (84.0%)120 (91.6%)
     Unknown2 (0.4%)0 (0%)
    Fasting blood glucose (mg/dL), mean (range)133.95 (60–303)127.84 (79–209)0.32
    Surgeries before index operation (count), mean (range)
     Ever0.58 (0–12)0.61 (0–14)0.39
     90 d Prior0.07 (0–5)0.02 (0–1)0.13
    Direct cost of operative supplies and implants ($), mean (range)10,254 (116–50,894)6696 (342–27,592) <0.001
    Length of hospital stay (h), mean (range)104.64 (24–1070)96.59 (26–563) 0.006
    Length of follow-up (mo), mean (range)43.62 (0.5–83.11)38.24 (0.7–80.74) 0.018
    Non-neurosurgical operations 30 d after index operation (count), mean (range)0.07 (0–3)0.09 (0–2)0.31
    • Note: Statistically significant (P < 0.05) values are bolded.

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    Table 2

    Characteristics of the subset of patients with the least amount of overlap (bottom 40% of patients with overlap) and the most amount of overlap (top 10% of patients with overlap), subsequently matched on demographic variables but not the operating surgeon.

    VariableLeast Overlap (N = 79)Most Overlap (N = 79) P Value
    Age (y), mean (range)61.96 (24–79)63.20 (26–79)0.50
    Gender, n (%)>0.99
     Male32 (40.5%)32 (40.5%)
     Female47 (59.5%)47 (59.5%)
    Race, n (%)>0.99
     Black2 (2.5%)2 (2.5%)
     White77 (97.5%)77 (97.5%)
    Insurance, n (%)0.53
     Commercial3 (3.8%)1 (1.3%)
     Medicare39 (49.4%)42 (53.2%)
     Medicaid4 (5.1%)1 (1.3%)
     Managed care22 (27.8%)21 (26.6%)
     Blue cross11 (13.9%)14 (17.7%)
    Tobacco use within past 12 mo, n (%)>0.99
     Yes1 (1.3%)1 (1.3%)
     No78 (98.7%)78 (98.7%)
    Fasting blood glucose (mg/dL), mean (range)136.26 (92–222)128.48 (79–207)0.35
    Surgeries before index operation (count), mean (range)
     Ever0.19 (0–4)0.14 (0–4)0.98
     90 d Prior0.03 (0–2)0.01 (0–1)>0.99
    Direct cost of operative supplies and implants ($), mean (range)10,606 (960–42,850)6029 (342–20,689) <0.001
    Length of hospital stay (h), mean (range)106.43 (48–400)84.92 (26–367) 0.001
    Length of follow-up (mo), mean (range)43.36 (3.75–81.27)40.16 (0.66–80.75)0.41
    Non-neurosurgical operations 30 d after index operation (count), mean (range)0.04 (0–1)0.08 (0–1)0.31
    • Note: Statistically significant (P < 0.05) values are bolded.

    • View popup
    Table 3

    Characteristics of the subset of patients with the least amount of overlap (bottom 40% of patients with overlap) and the most amount of overlap (top 10% of patients with overlap), subsequently matched on both demographic variables and limited to the same operating surgeon.

    VariableLeast Overlap (N = 34)Most Overlap (N = 34) P Value
    Age (y), mean (range)56.74 (24–76)58.26 (26–76)0.64
    Gender, n (%)>0.99
     Male19 (55.9%)19 (55.9%)
     Female15 (44.1%)15 (44.1%)
    Race, n (%)>0.99
     Black1 (2.9%)1 (2.9%)
     White33 (97.1%)33 (97.1%)
    Insurance, n (%)0.20
     Commercial4 (11.8%)0 (0%)
     Medicare12 (35.3%)13 (38.2%)
     Medicaid2 (5.9%)1 (2.9%)
     Managed care11 (32.4%)10 (29.4%)
     Blue cross5 (14.7%)10 (29.4%)
    Tobacco use within past 12 mo, n (%)>0.99
     Yes1 (2.9%)1 (2.9%)
     No33 (97.1%)33 (97.1%)
    Fasting blood glucose (mg/dL), mean (range)122.48 (92–174)128.73 (79–207)0.46
    Surgeries before index operation (count), mean (range)
     Ever0.44 (0–10)0.24 (0–4)0.98
     90 d Prior0.06 (0–2)0.03 (0–1)>0.99
    Direct cost of operative supplies and implants ($), mean (range)7120 (116–26,035)6400 (342–17,459)0.75
    Length of hospital stay (h), mean (range)86.73 (25–242)69.65 (31–151)0.10
    Length of follow-up (mo), mean (range)34.84 (3.0–78.44)41.42 (1.3–77.69)0.21
    Non-neurosurgical operations 30 d after index operation (count), mean (range)0.12 (0–1)0.09 (0–1)0.70
    • View popup
    Table 4

    Short-term outcome data analyzing the impact of increasing duration of overlap as a continuous variable. Exact-matched patients with the most amount of overlap (top 10%) and least amount of overlap (bottom 40%) were also compared.

    30-d OutcomesIncreasing Duration of OverlapAfter Exact Match Not Limited by SurgeonAfter Exact Match Limited by Surgeon
    Readmission P = 0.91
    1.00 (0.99–1.01)
    P > 0.99
    1.00 (0.17–5.82)
    P = 0.69
    0.67 (0.08–4.48)
    Reoperation P = 0.91
    1.00 (0.99–1.01)
    P = 0.38
    3.00 (0.32–78.99)
    P = 0.69
    1.50 (0.22–12.61)
    Emergency department visits P = 0.41
    1.00 (0.99–1.01
    P = 0.63
    0.50 (0.02–6.57)
    P = 0.69
    0.67 (0.08–4.48)
    Mortality P = 0.90
    1.00 (0.94–1.05)
    N/AN/A
    Morbidity P = 0.70
    1.00 (0.99–1.01)
    P = 0.51
    0.60 (0.12–2.60)
    P = 0.51
    0.60 (0.12–2.60)
    Morbidity/surgical complication P = 0.78
    1.00 (0.99–1.01)
    P = 0.39
    0.57 (0.15–1.97)
    P = 0.34
    0.50 (0.10–2.01)
    • Note: Data are presented as OR (95% CI).

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Increasing Nonconcurrent Overlapping Surgery Is Not Associated With Outcome Changes in Lumbar Fusion
Ali S. Farooqi, Austin J. Borja, Donald K.E.D. Detchou, Gregory Glauser, Krista Strouz, Scott D. McClintock, Neil R. Malhotra
International Journal of Spine Surgery Aug 2022, 16 (4) 651-659; DOI: 10.14444/8305

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Increasing Nonconcurrent Overlapping Surgery Is Not Associated With Outcome Changes in Lumbar Fusion
Ali S. Farooqi, Austin J. Borja, Donald K.E.D. Detchou, Gregory Glauser, Krista Strouz, Scott D. McClintock, Neil R. Malhotra
International Journal of Spine Surgery Aug 2022, 16 (4) 651-659; DOI: 10.14444/8305
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