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Research ArticleBiologics

Evolution of Bioactive Implants in Lateral Interbody Fusion

Julie L. Chan, Hyun W. Bae, S. Harrison Farber, Juan S. Uribe, Robert K. Eastlack and Corey T. Walker
International Journal of Spine Surgery April 2022, 16 (S1) S61-S68; DOI: https://doi.org/10.14444/8237
Julie L. Chan
1 Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA
MD, PhD
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Hyun W. Bae
2 Department of Orthopedic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA
MD
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S. Harrison Farber
3 Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA
MD
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Juan S. Uribe
3 Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA
MD
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Robert K. Eastlack
4 Department of Orthopedic Surgery, Scripps Clinic, La Jolla, CA, USA
MD
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Corey T. Walker
1 Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA
MD
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    Figure 1

    The 1-y sagittal (A, C) and coronal (B, D) computed tomography postoperative images demonstrating lumbar lateral interbody fusion with polyetheretherketone (A, B) (Coroent XL, Nuvasive, San Diego, CA) and 3-dimensional-printed titanium cages (C, D) (Modulus, Nuvasive, San Diego, CA).

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    Figure 2

    Lateral (A) and anteroposterior (B) x-ray imaging and sagittal (C) and coronal (D) computed tomography images of a patient treated with a block titanium transforaminal lumbar interbody implant 4 y prior. Note the subsidence of the superior end plate of L5 and the extensive radiographic artifact making evaluation of arthrodesis difficult. The absence of haloing around the pedicle screws to suggest screw loosening makes fusion seem probable, and dynamic imaging from this patient showed no excessive motion.

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    Table

    Comparison of implant characteristics among different materials utilized in interbody cages.

    Implant MaterialEffective Modulus (GPa)7–11 PorositySurface ChemistryTopographyShear Resistance
    Cortical bone18+++Yes
    PEEK4−−−Yes
    Ti110+/−++/−Yes
    Ti-coated PEEK110+/−++No
    Three-dimensional-printed Ti0.9–2.5+++Yes
    • Characteristics of each implant are designated by −, +/−, or +. Minimal to no effect of a characteristic is designated by “−”, while “+/−” indicates the characteristic varies dependent on the construct, and “+” designates those implants that possess the characteristic.

    • PEEK, polyetheretherketone; Ti, titanium.

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International Journal of Spine Surgery: 16 (S1)
International Journal of Spine Surgery
Vol. 16, Issue S1
1 Apr 2022
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Evolution of Bioactive Implants in Lateral Interbody Fusion
Julie L. Chan, Hyun W. Bae, S. Harrison Farber, Juan S. Uribe, Robert K. Eastlack, Corey T. Walker
International Journal of Spine Surgery Apr 2022, 16 (S1) S61-S68; DOI: 10.14444/8237

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Evolution of Bioactive Implants in Lateral Interbody Fusion
Julie L. Chan, Hyun W. Bae, S. Harrison Farber, Juan S. Uribe, Robert K. Eastlack, Corey T. Walker
International Journal of Spine Surgery Apr 2022, 16 (S1) S61-S68; DOI: 10.14444/8237
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  • Article
    • Abstract
    • INTRODUCTION
    • IMPLANT CAGES
    • IMPLANT MODIFICATIONS
    • BIOACTIVE IMPLANTS FOR LATERAL INTERBODY FUSION
    • CONCLUSION
    • Footnotes
    • References
  • Figures & Data
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Cited By...

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More in this TOC Section

  • Stem Cells Therapy as a Treatment for Discogenic Low Back Pain: A Systematic Review
  • Does Bone Morphogenetic Protein Use Reduce Pseudarthrosis Rates in Single-Level Transforaminal Lumbar Interbody Fusion Surgeries?
  • Editors’ Introduction: The Role of Bioactive Materials in the Future of Spine Surgery
Show more Biologics

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Keywords

  • bioactive implants
  • surface technology
  • osseointegration
  • titanium
  • PEEK
  • fusion
  • subsidence
  • biologics

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