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Research ArticleMinimally Invasive Surgery

Clinical Outcomes of Prone Transpsoas Lumbar Interbody Fusion: A 1-Year Follow-Up

Hardeep Singh, Ian Wellington, Francine Zeng, Christopher Antonacci, Michael Mancini, Mirghani Mohamed, Joellen Broska, Scott Mallozzi and Isaac Moss
International Journal of Spine Surgery August 2024, 18 (4) 400-407; DOI: https://doi.org/10.14444/8625
Hardeep Singh
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MD
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  • For correspondence: hasingh@uchc.edu
Ian Wellington
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MD
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Francine Zeng
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MD
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Christopher Antonacci
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MD
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Michael Mancini
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MD
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Mirghani Mohamed
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
BS
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Joellen Broska
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MPH
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Scott Mallozzi
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MD
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Isaac Moss
1 Department of Orthopedic Surgery, University of Connecticut Health Center, Comprehensive Spine Center, Farmington, CT, USA
MDCM, MASᴄ, FRCSC
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  • Article
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Article Figures & Data

Figures

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  • Figure 1
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    Figure 1

    Function Global Rating of Change (GROC) postoperative scores at 2 wk, 6 wk, 3 mo, and 1 y.

  • Figure 2
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    Figure 2

    Pain Global Rating of Change (GROC) postoperative scores at 2 wk, 6 wk, 6 mo, and 1 y.

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    Figure 3

    Patient-acceptable symptom state (PASS) postoperative scores at 2 wk, 6 wk, 6 mo, and 1 y.

Tables

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    Table 1

    Demographics of study participants.

    Characteristics n (%)
    No. of patients97
    No. of levels161
    No. of PTP levels
     155 (57)
     229 (30)
     36 (6)
     47 (7)
    No. of PTP levels
     229 (30)
     36 (6)
     47 (7)
    Total No. of levels fused
     140 (41)
     225 (26)
     315 (16)
     415 (16)
     5+2 (2)
    Level of PTP
     L1−L218 (11)
     L2−L334 (21)
     L3−L453 (33)
     L4−L556 (35)
    No. of transforaminal lumbar interbody fusion levels
     076 (79)
     115 (16)
     25 (5)
     31 (1)
    No. of anterior lumbar interbody fusion levels
     094 (97)
     12 (2)
     21 (1)
    Gender, female54 (56)
    Age, y, mean (SD)62 (11)
    Body mass index, mean (SD)30 (7)
    Comorbidities
     Hypertension69 (71)
     Hyperlipidemia42 (43)
     Diabetes18 (19)
     Coronary artery disease9 (9)
     Congestive heart failure1 (1)
     Chronic obstructive pulmonary disease11 (11)
     Chronic kidney disease6 (6)
    ASA classification
     12 (2)
     258 (60)
     337 (37)
    • Abbreviations: ASA, American Society of Anesthesiology; PTP, prone transpsoas.

    • Note: Data presented as n (%) unless otherwise indicated.

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    Table 2

    Mean (SD) change in radiographic parameters.

    Radiographic Measurement N Mean (SD) Change Compared With Preoperation P
    LL (°)95
     Initial postoperative2 (10)0.049
     1 y postoperative3 (9)0.005
    SL (°)155
     Initial postoperative6 (5)<0.001
     1 y postoperative5 (5)<0.001
    ADH (mm)155
     Initial postoperative8 (4)<0.001
     1 y postoperative7 (4)<0.001
    PDH (mm)155
     Initial postoperative3 (2)< 0.001
     1 y postoperative3 (2)< 0.001
    • Abbreviations: ADH, anterior disc height; LL, lumbar lordosis; PDH, posterior disc height; SL, segmental lordosis.

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    Table 3

    Mean (SD) change in patient-reported outcomes.

    Patient-Reported Outcomes n Mean (SD) Change Compared With Preoperation P
    ODI
     2 wk413.7 (22.8)0.307
     6 wk48−8.7 (18.3)0.002
     6 mo45−24.2 (15.1)<0.001
     1 y42−21.7 (19.6)<0.001
    Pain EQ5D
     2 wk430.00 (0.21)0.9
     6 wk510.12 (0.2)<0.001
     6 mo470.17 (0.2)<0.001
     1 y450.19 (0.3)<0.001
    Leg VAS
     2 wk48−2.6 (3.9)<0.001
     6 wk52−3.5 (3.5)<0.001
     6 mo48−4.6 (2.7)<0.001
     1 y46−4.4 (3.6)<0.001
    Back VAS
     2 wk48−1.7 (2.8)<0.001
     6 wk52−3.5 (2.7)<0.001
     6 mo48−4.3 (2.3)<0.001
     1 y46−4.2 (2.6)<0.001
    • Abbreviations: ODI, Oswestry Disability Index; VAS, visual analog scale.

    • View popup
    Table 4

    Postoperative complications of study participants.

    Complication n (%)
    Intraoperative complications 
     ALL rupture8 (8)
     Aborted prone transpsoas level2 (2)
    Postoperative neuromotor complications 
     Ipsilateral hip flexor pain45 (46)
     Ipsilateral hip flexor weakness57 (59)
     Ipsilateral thigh numbness23 (24)
     Contralateral hip flexor pain28 (29)
     Contralateral hip flexor weakness21 (22)
     Femoral nerve palsy2 (2)
    Postoperative medical complications 
     Urinary retention8 (8)
     Deep vein thrombosis1 (1)
     Pneumonia1 (1)
     Altered mental status5 (5)
     Urosepsis3 (3)
     Death2 (2)
    Other complications 
     Abdominal wall pseudohernia1 (1)
     Subsidence on 1-y radiographs6 (6)
    • Abbreviation: ALL, anterior longitudinal ligament.

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International Journal of Spine Surgery
Vol. 18, Issue 4
1 Aug 2024
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Clinical Outcomes of Prone Transpsoas Lumbar Interbody Fusion: A 1-Year Follow-Up
Hardeep Singh, Ian Wellington, Francine Zeng, Christopher Antonacci, Michael Mancini, Mirghani Mohamed, Joellen Broska, Scott Mallozzi, Isaac Moss
International Journal of Spine Surgery Aug 2024, 18 (4) 400-407; DOI: 10.14444/8625

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Clinical Outcomes of Prone Transpsoas Lumbar Interbody Fusion: A 1-Year Follow-Up
Hardeep Singh, Ian Wellington, Francine Zeng, Christopher Antonacci, Michael Mancini, Mirghani Mohamed, Joellen Broska, Scott Mallozzi, Isaac Moss
International Journal of Spine Surgery Aug 2024, 18 (4) 400-407; DOI: 10.14444/8625
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More in this TOC Section

  • Comparative Review of Lateral and Oblique Lumbar Interbody Fusion: Technique, Outcomes, and Complications
  • Key Considerations in Surgical Decision-Making on the Side of Approach for Lumbar Lateral Transpsoas Interbody Fusion Techniques
  • A Spine Surgeon’s Learning Curve With the Minimally Invasive L5 to S1 Lateral ALIF Surgical Approach: Perioperative Outcomes and Technical Considerations
Show more Minimally Invasive Surgery

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Keywords

  • lumbar stenosis
  • interbody fusion
  • prone-transpsoas
  • lateral
  • transpsoas
  • single-position surgery
  • lumbar plexus

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