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Research ArticleFull Length Article
Open Access

Biomechanical assessment and fatigue characteristics of an articulating nucleus implant

Nathaniel R. Ordway, William F. Lavelle, Tim Brown and Q-Bin Bao
International Journal of Spine Surgery January 2013, 7 e109-e117; DOI: https://doi.org/10.1016/j.ijsp.2013.10.001
Nathaniel R. Ordway
aDepartment of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY
MS
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  • For correspondence: ordwayn@upstate.edu
William F. Lavelle
aDepartment of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY
MD
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Tim Brown
bPioneer Surgical Technology, Marquette, MI
MS
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Q-Bin Bao
cBonovo Orthopedics, Beijing, P R China
PhD
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  • Article
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Article Figures & Data

Figures

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  • Fig. 1
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    Fig. 1

    Articulating PEEK nucleus replacement used in this study.

  • Fig. 2
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    Fig. 2

    Radiographic image of trial spacer for sizing of the nucleus implant in (A) AP and (B) lateral views.

  • Fig. 3
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    Fig. 3

    Biomechanical test setup of an example test specimen in left lateral bending before fatigue test protocol.

  • Fig. 4
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    Fig. 4

    Macroscopic cross-section of the intervertebral disc following fatigue testing of 100(k) cycles for (A) an intact, untreated disc and (B) an implanted disc.

  • Fig. 5
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    Fig. 5

    Mean loss in disc height (mm) at peak compressive load for the 3 disc conditions.

  • Fig. 6
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    Fig. 6

    CT slice of an L1 vertebra. There are superior and inferior endplate fractures (shown by red arrows), all of which are likely to be chronic given the intact cortex. Notice the small osteophytes (yellow arrow) at the inferior endplate. A 3D reconstruction (not shown) confirmed these observations.

  • Fig. 7
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    Fig. 7

    CT slice of a L1 vertebra. Fracture of the endplate (shown by red arrow) at the control level.

Tables

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    Table 1

    Specimen information (N = 6)

    SpecimenGenderAgeBMD (g/cm3)Disc depth (cm)Disc width (cm)Disc area (cm2)Percenatge of implant/disc area
    7761 (T12-L2)M541.5384.115.4317.8410.65
    7761 (L3-5)M541.5384.076.3720.029.49
    7827 (T12-L2)M580.7863.795.2115.5315.52
    7827 (L3-5)M580.7863.985.3617.5713.72
    7760 (T12-L2)M650.9193.735.4516.9914.18
    7760 (L3-5)M650.9193.745.4316.5114.60
    Mean591.0813.905.5417.4113.03
    St. dev.50.3590.170.421.522.39
    • Abbreviations: BMD, bone mineral density; St. dev., standard deviation.

    • View popup
    Table 2

    Mean ROM values (degrees) for the torsion test mode in the conditions tested

    ModeIntactDiscectomyImplant
    Left torsion2.46 ± 0.542.75 ± 0.292.62 ± 0.42
    Right torsion2.50 ± 0.512.80 ± 0.272.61 ± 0.38
    • View popup
    Table 3

    Mean ROM values (degrees) for the sagittal and coronal bending test modes in the conditions tested

    ModeLevelIntactDiscectomyImplant
    FlexionControl
    Surgical
    3.59 ± 0.61
    3.51 ± 0.80
    3.67 ± 0.54
    4.55 ± 1.57
    3.42 ± 0.60
    4.07 ± 1.66
    ExtensionControl
    Surgical
    2.44 ± 1.17
    2.77 ± 1.14
    2.34 ± 1.14
    1.80 ± 0.81*
    2.33 ± 1.28
    2.59 ± 0.98
    Left bendControl
    Surgical
    2.73 ± 0.70
    3.42 ± 0.99
    2.67 ± 0.69
    3.35 ± 1.21
    2.71 ± 0.68
    3.04 ± 1.11
    Right bendControl
    Surgical
    2.64 ± 0.74
    3.20 ± 0.95
    2.65 ± 0.79
    3.49 ± 1.09
    2.64 ± 0.80
    3.78 ± 1.46
    • ↵* Denotes significant difference (P < .05) from intact.

    • View popup
    Table 4

    Mean stiffness values for the pure compression and torsion test modes in the conditions tested

    ModeIntactDiscectomyImplant
    Pure comp (N/mm)1485 ± 2291364 ± 2351362 ± 241
    Left torsion (Nmm/degree)4056 ± 6003610 ± 4253848 ± 316
    Right torsion (Nmm/degree)3696 ± 4933259 ± 2433518 ± 278
    • View popup
    Table 5

    Mean stiffness values (N = 6) for the sagittal and coronal bending test modes (Nmm/degree)

    ModeLevelIntactDiscectomyImplant
    FlexionControl
    Surgical
    4168 ± 566
    4785 ± 1437
    3804 ± 360
    4817 ± 1220
    4034 ± 627
    4911 ± 1432
    ExtensionControl
    Surgical
    6032 ± 2148
    4759 ± 2441
    6754 ± 2220
    8925 ± 5397*
    5983 ± 1640
    5904 ± 2632
    Left bendControl
    Surgical
    4557 ± 1214
    3566 ± 869
    4578 ± 1294
    4191 ± 1098
    4522 ± 1283
    4594 ± 1092
    Right bendControl
    Surgical
    4764 ± 1658
    3923 ± 1260
    4738 ± 1720
    4310 ± 1150
    4731 ± 1711
    4006 ± 1097
    • ↵* Denotes significant difference (P < .05) from intact.

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1 Jan 2013
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Biomechanical assessment and fatigue characteristics of an articulating nucleus implant
Nathaniel R. Ordway, William F. Lavelle, Tim Brown, Q-Bin Bao
International Journal of Spine Surgery Jan 2013, 7 e109-e117; DOI: 10.1016/j.ijsp.2013.10.001

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Biomechanical assessment and fatigue characteristics of an articulating nucleus implant
Nathaniel R. Ordway, William F. Lavelle, Tim Brown, Q-Bin Bao
International Journal of Spine Surgery Jan 2013, 7 e109-e117; DOI: 10.1016/j.ijsp.2013.10.001
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Keywords

  • lumbar spine
  • Intervertebral disc
  • nucleus replacement
  • disc height
  • Lateral bending
  • range of motion

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