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Research ArticleArticle
Open Access

Five and Ten Year Follow-up on Intradiscal Ozone Injection for Disc Herniation

Josip Buric, Luca Rigobello and David Hooper
International Journal of Spine Surgery January 2014, 8 17; DOI: https://doi.org/10.14444/1017
Josip Buric
1Villa Torri Hospital, Bologna, Italy
MD
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Luca Rigobello
2Department for Neurosurgery University of Padua, Padova, Italy
MD
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David Hooper
3Minimus Spine, Inc. Austin, TX
PhD
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  • Fig. 1
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    Fig. 1

    Time course of operations following ozone treatment. The blue line represents actual responses from patients contacted. The red line indicates a worst-case scenario where all patients lost to follow-up went on to surgery.

  • Fig. 2
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    Fig. 2

    MRIs from two patients showing a reduction in the volume of the disc herniation after intradiscal ozone injection.

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    Table 1

    Summary of Operations and Clinical Outcomes in patients not requiring surgery.

    5 years10 years
    Elected for Surgery18%18%
    Of those not electing for surgery…
    Much Better46.6%43.3%
    Better36.4%45.0%
    Same6.8%8.3%
    Worse10.2%3.3%
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International Journal of Spine Surgery
Vol. 8
1 Jan 2014
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Five and Ten Year Follow-up on Intradiscal Ozone Injection for Disc Herniation
Josip Buric, Luca Rigobello, David Hooper
International Journal of Spine Surgery Jan 2014, 8 17; DOI: 10.14444/1017

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Five and Ten Year Follow-up on Intradiscal Ozone Injection for Disc Herniation
Josip Buric, Luca Rigobello, David Hooper
International Journal of Spine Surgery Jan 2014, 8 17; DOI: 10.14444/1017
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