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Research ArticleLumbar Spine

Three- and 4-Level Lumbar Arthrodesis Using Adjunctive Pulsed Electromagnetic Field Stimulation: A Multicenter Retrospective Evaluation of Fusion Rates and a Review of the Literature

Vikas V. Patel, James Billys, David O. Okonkwo, David Y. He, James T. Ryaby and Kris Radcliff
International Journal of Spine Surgery March 2021, 8031; DOI: https://doi.org/10.14444/8031
Vikas V. Patel
1Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, Colorado
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James Billys
2The Back Center, Melbourne, Florida
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David O. Okonkwo
3University of Pittsburgh, Pittsburgh, Pennsylvania
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David Y. He
4Analytical Solutions Group, Inc, North Potomac, Maryland
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James T. Ryaby
5Orthofix, Inc, Lewisville, Texas
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Kris Radcliff
6Rothman Institute, Egg Harbor Township, New Jersey
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ABSTRACT

Background The incidence of 3- and 4-level lumbar arthrodesis is rising due to an aging population, and fusion rates affect clinical success in this population. Pulsed electromagnetic field (PEMF) stimulation is used as an adjunct to increase fusion rates following multilevel arthrodesis. The purpose of the study was to evaluate the fusion rates for subjects who underwent 3- and 4-level lumbar interbody arthrodesis following PEMF treatment.

Methods In this retrospective, multicenter study, patient charts that listed 3- or 4-level lumbar arthrodesis with adjunctive use of a PEMF device were evaluated. Inclusion criteria included patients who were diagnosed with lumbar degenerative disease, spinal stenosis, and/or spondylolisthesis (grade 1 or 2). A radiographic evaluation of fusion status was performed at 12 months by the treating physicians. Fusion rates were stratified by graft material, surgical interbody approach, and certain clinical risk factors for pseudoarthrosis.

Results A total of 55 patients were identified who had a 12-month follow-up. The radiographic fusion rate was 92.7% (51 patients) at 12 months. There were no significant differences in fusion rates for patients treated with allograft or autograft, for patients with different interbody approaches, or for those with or without certain clinical risk factors.

Conclusions With modern fusion techniques and PEMF, the overall fusion rate was high following 3- and 4-level lumbar arthrodesis.

Level of Evidence 4.

Clinical Relevance PEMF may be a useful adjunct for treatment of patients with surgical risk factors, such as multilevel arthrodesis, and clinical risk factors.

  • pulsed electromagnetic field stimulation
  • lumbar arthrodesis
  • adjunctive therapy
  • spinal fusion
  • bone stimulation
  • lumbar fusion
  • pseudarthrosis
  • failed fusion

Footnotes

  • Disclosures and COI: The study was funded by Orthofix. V.V.P., J.B., and D.O.O. received Orthofix funding to support clinical research. K.R. did not receive funding for this study from Orthofix. D.Y.H. is a consultant of Orthofix. J.T.R. is employed by and owns stock in Orthofix.

  • This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery. Copyright © 2021 ISASS
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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Three- and 4-Level Lumbar Arthrodesis Using Adjunctive Pulsed Electromagnetic Field Stimulation: A Multicenter Retrospective Evaluation of Fusion Rates and a Review of the Literature
Vikas V. Patel, James Billys, David O. Okonkwo, David Y. He, James T. Ryaby, Kris Radcliff
International Journal of Spine Surgery Mar 2021, 8031; DOI: 10.14444/8031

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Three- and 4-Level Lumbar Arthrodesis Using Adjunctive Pulsed Electromagnetic Field Stimulation: A Multicenter Retrospective Evaluation of Fusion Rates and a Review of the Literature
Vikas V. Patel, James Billys, David O. Okonkwo, David Y. He, James T. Ryaby, Kris Radcliff
International Journal of Spine Surgery Mar 2021, 8031; DOI: 10.14444/8031
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Keywords

  • pulsed electromagnetic field stimulation
  • lumbar arthrodesis
  • adjunctive therapy
  • spinal fusion
  • bone stimulation
  • lumbar fusion
  • pseudarthrosis
  • failed fusion

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