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Research ArticleMinimally Invasive Surgery

Multilevel Minimally Invasive Lumbar Decompression: Clinical Efficacy and Durability to 2 Years

Ryan Khanna, Hani Malone, Kavantissa M. Keppetipola, Harel Deutsch, Richard G. Fessler, Ricardo B. Fontes and John E. O'Toole
International Journal of Spine Surgery July 2021, 8102; DOI: https://doi.org/10.14444/8102
Ryan Khanna
1Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois
MD, MBA, MSCI
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Hani Malone
2Department of Neurosurgery, Scripps Clinic, La Jolla, California
MD
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Kavantissa M. Keppetipola
1Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois
MD
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Harel Deutsch
1Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois
MD
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Richard G. Fessler
1Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois
MD, PhD
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Ricardo B. Fontes
1Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois
MD, PhD
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John E. O'Toole
1Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois
MD, MS
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ABSTRACT

Background The clinical efficacy of single-level minimally invasive lumbar decompression and/or microdiscectomy is well established, with improved postoperative functional outcome and pain scores. However, there is a paucity of clinical data supporting the use of minimally invasive (MIS) techniques in a single operation to address pathology at multiple lumbar levels, and this study attempts to address this issue.

Methods A retrospective review of prospectively collected data from patients with symptomatic lumbar stenosis and/or disc herniations who underwent multilevel minimally invasive decompression or microdiscectomy from November 2014 to February 2018 was conducted at a single academic medical center. Patient-reported outcome measures (PROMs), including the Oswestry Disability Index (ODI), visual analog scale (VAS) for back and leg pain, 12-Item Short Form Health Survey (SF-12) Physical Component Summary Score (PCS) and Mental Component Summary Score (MCS), and Scoliosis Research Society survey (SRS-30), were prospectively collected before surgery and at 3 months, 6 months, 1 year, and 2 years postoperatively.

Results During the study period, 92 patients received multilevel (≥ 2 level) MIS lumbar decompression and/or discectomy (69 two level, 21 three level, 2 four level). The mean age at surgery was 69.7 years, and 23 (25%) patients were women. Patient-reported outcomes were significantly improved both in the short and long term except for the SF-12 MCS. Average improvement from baseline was (at 3 months and 2 years, respectively): VAS back, −3.9 and −2.8; VAS leg, −3.6 and −2.6; ODI, −13 and −14.6; SF-12 MCS, 2.8 and −0.3; SF-12 PCS, 6.9 and 10.1; and SRS-30, 0.57 and 0.55. Minimal clinically important difference for the study population was reached for every PROM except SF-12 MCS. Surgical complications occurred in 16 patients (17.4%), and 8 patients (8.6%) required postoperative fusions within 2 years.

Conclusion The use of MIS techniques to perform lumbar decompression and/or discectomy at multiple levels was found to be both clinically effective and durable. Fusion rates remained low 2 years after the index surgery and were consistent with literature data for open procedures.

Level of Evidence 2.

  • MIS
  • minimally invasive
  • decompression
  • discectomy
  • multilevel
  • laminectomy
  • PROM

Footnotes

  • Disclosures and COI: No financial support was required for this study. The authors report no conflicts of interest.

  • This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery. Copyright © 2021 ISASS
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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Multilevel Minimally Invasive Lumbar Decompression: Clinical Efficacy and Durability to 2 Years
Ryan Khanna, Hani Malone, Kavantissa M. Keppetipola, Harel Deutsch, Richard G. Fessler, Ricardo B. Fontes, John E. O'Toole
International Journal of Spine Surgery Jul 2021, 8102; DOI: 10.14444/8102

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Multilevel Minimally Invasive Lumbar Decompression: Clinical Efficacy and Durability to 2 Years
Ryan Khanna, Hani Malone, Kavantissa M. Keppetipola, Harel Deutsch, Richard G. Fessler, Ricardo B. Fontes, John E. O'Toole
International Journal of Spine Surgery Jul 2021, 8102; DOI: 10.14444/8102
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  • Comparative Review of Lateral and Oblique Lumbar Interbody Fusion: Technique, Outcomes, and Complications
  • A Spine Surgeon’s Learning Curve With the Minimally Invasive L5 to S1 Lateral ALIF Surgical Approach: Perioperative Outcomes and Technical Considerations
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Keywords

  • MIS
  • minimally invasive
  • decompression
  • discectomy
  • multilevel
  • laminectomy
  • PROM

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