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Research ArticleNovel Techniques & Technology

Elective Spinal Transpedicular Ablation of the Basivertebral Nerve of the Vertebral Segment in Adult Spinal Deformity Patients

Guy Fogel, Jake Dickinson and Sunny Vuong
International Journal of Spine Surgery August 2024, 8632; DOI: https://doi.org/10.14444/8632
Guy Fogel
1 Christus Santa Rosa Spine Clinic, San Antonio, TX, USA
MD
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  • For correspondence: gfogelmd@gmail.com
Jake Dickinson
2 University of Texas Health Science Center San Antonio, San Antonio, TX, USA
MD
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Sunny Vuong
3 Yale University New Haven Connecticut, New Haven, CT, USA
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    Figure 1

    Anteroposterior (A) and lateral (B) conventional radiographs of the lumbar spine taken in a 73-year-old patient with a 15° lumbar scoliosis (A; white lines Cobb angle measurement) and L4–L5 lateral spondylolisthesis (white arrow). (B) Loss of lumbar lordosis (white line). After basivertebral nerve ablation L1–S1 with previous laminectomy. The patient had good improvement of Oswestry Disability Index (60 points) to 24 points (moderate disability of daily activities) and VAS (6 cm) to 2 cm at the last follow-up.

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    Figure 2

    (A) Lateral x-ray retrolisthesis with disc narrowing seen at L5–S1 in 42-year-old nurse. (B) Sagittal T2-weighted, short TI inversion recovery, and T1 weighted magnetic resonance images show Modic 1 changes of L5 and S1 with modrate-severe disc degeneration. This spondylolisthesis without pars defect responded well to basivertebral nerve ablation. The preoperative visual analog scale score of 8 cm improved to 1 cm and Oswestry Disability Index improved from 52 to 10 points.

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    Figure 3

    Sagittal T2-weighted (A), short TI inversion recovery (B), and sagittal T1 weighted (C) magnetic resonance images of a patient with old injury from parachuting. Panels A, B, and C show Modic 1 and Modic 2 changes around Schmorl’s nodes at L1–L4 (white arrows at each VEP disruption). After basivertebral nerve ablation L1–L5, the visual analog scale improved 8 cm to 0 and the Oswestry Disability Index improved 40 points from 52 to 10 at the last follow-up.

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    Figure 4

    Anteroposterior (A) and lateral (B) conventional radiographs of the lumbar spine taken in a 79-year-old patient (A) with a 15° lumbar scoliosis (white lines Cobb angle measurement). (B) Sagittal imbalance with loss of lumbar lordosis (white curved line; pelvic tilt [PT] = 37, pelvic incidence [PI] = 54.4, PI–L1 = 30.7). (C) sagittal T1 and (D) T2-weighted magnetic resonance images of same patient show Modic 1 and Modic 2 changes around Schmorl’s nodes vertebral endplate (VEP) damage at L1–L4 (white arrows at each VEP disruption in panels C and D). (E) T2-weighted axial image shows severe central and foraminal stenosis. This patient refused corrective subtraction osteotomy or laminectomy. After basivertebral nerve ablation (BVNA) L2–S1, VAS improved 9 cm (from 10 to 1) and Oswestry Disability Index improved 58 points (from 70 to 12) at the last follow-up. The patient was very satisfied with the BVNA result and said he would not do an osteotomy.

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    Table 1

    Demographics of study participants.

    DemographicsGroup A (n = 41)Group B (n = 77)
    Women, n (%)1844
    Men, n (%)2333
    Age, y, mean (range)68 (40–90)71 (43–88)
    Working before BVNA1218
    CLBP ≥2 y41 (100%)74 (96%)
    Opioid use, preoperative9 (22%)9 (11%)
    VAS score, preoperative, mean (range)9 (5–10)9 (7–10)
    ODI score, preoperative, mean (range)53 (32–78)58 (19–80)
    • Abbreviations: BVNA, basivertebral nerve ablation; CLBP, chronic low back pain; ODI, Oswestry Disability Index; VAS, visual analog scale.

    • View popup
    Table 2

    Imaging review.

    Adult Spinal DeformityGroup A, n (%)Group B, n (%)
    Scoliosis33 (80)54 (70)
    Severe scoliosis (>20°)2 (5)4 (5)
    Loss of sagittal balance3 (7)9 (12)
    Spondylolisthesis39 (95)54 (70)
    Spondylolisthesis + mobility022 (29)
    Stenosis12 (29)33 (43)
    Previous laminectomy7 (17)17 (22)
    Previous fusion010 (13)
    Previous vertebroplasty1 (2)1 (1)
    • View popup
    Table 3

    Post-BVNA results.

    After BVNAGroup AGroup B
    Total No. of BVNA levels167336
    L2 level included, n 1740
    Opioid use at LFU, n (%)5 (12%)15 (20%)
    Fusion recommended after BVNA, n (%)017 (22%)
    VAS score at LFU, mean (range)2 (0–5)3 (0–10)
    ODI score at LFU, mean (range)14 (0–52)29 (0–78)
    Interval to LFU, d, mean (range)261 (11–844)300 (6–783)
    • Abbreviations: BVNA, basivertebral nerve ablation; LFU, last follow-up; ODI, Oswestry Disability Index; VAS, visual analog scale.

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    Table 4

    Complications.

    ComplicationsGroup AGroup B
    Posterior column pain (radiculopathy, facet, sacroiliac joint, and hip)5 (12)21 (27)
    Nonspecific CLBP1 (2)15 (19)
    Stenosis radiculopathy peripheral neuropathy2 (5)22 (28)
    SI joint pain08 (10)
    SI fusion performed02 (3)
    VCF fragility fracture09 (13)
    Fusion recommended017 (22)
    Fusion performed01 (1)
    Revision BVNA1 (2)1 (1)
    Failed revision BVNA01 (1)
    • Abbreviations: BVNA, basivertebral nerve ablation; CLBP, chronic low back pain; VCF, vertebral compression fracture.

    • View popup
    Table 5

    Results in Group B subgroups.

    Subgroups in Group B n VAS Score, PreoperativeVAS Score, LFUODI Score, PreoperativeODI Score, PostoperativeLFU, d
    Adjacent to previous fusion12924125309
    Sagittal imbalance9936219125
    Laminectomy26925221283
    Fusion recommended after BVNA22946437300
    Removal pedicle screws5935729183
    Mobile spondylolisthesis21935528264
    Osteoporotic fracture VCF81046547370
    • Abbreviations: BVNA , basivertebral nerve ablation; LFU, last follow-up; ODI, Oswestry Disability Index; VAS, visual analog scale; VCF, vertebral compression fracture.

    • Note: VAS, ODI, and LFU data are presented as means. VAS was measured on a 10-cm scale. ODI was measured on a 100-point scale.

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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Elective Spinal Transpedicular Ablation of the Basivertebral Nerve of the Vertebral Segment in Adult Spinal Deformity Patients
Guy Fogel, Jake Dickinson, Sunny Vuong
International Journal of Spine Surgery Aug 2024, 8632; DOI: 10.14444/8632

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Elective Spinal Transpedicular Ablation of the Basivertebral Nerve of the Vertebral Segment in Adult Spinal Deformity Patients
Guy Fogel, Jake Dickinson, Sunny Vuong
International Journal of Spine Surgery Aug 2024, 8632; DOI: 10.14444/8632
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Keywords

  • chronic low back pain
  • basivertebral nerve ablation
  • radiofrequency
  • endplate degeneration
  • Modic changes
  • community practice setting

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