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Research ArticleLumbar Spine

Effects of Body Mass Index on Spondylolisthesis Surgery and Associated Patient-Reported Outcomes: A Retrospective Review

Rafael Garcia, Kari Odland and Jonathan Sembrano
International Journal of Spine Surgery April 2025, 8752; DOI: https://doi.org/10.14444/8752
Rafael Garcia
1 Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, USA
BS
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  • ORCID record for Rafael Garcia
  • For correspondence: garca147@umn.edu
Kari Odland
1 Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, USA
DAT, ATC
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Jonathan Sembrano
1 Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, USA
MD
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Article Figures & Data

Figures

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  • Figure 1
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    Figure 1

    Study flow chart.

  • Figure 2
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    Figure 2

    Visual analog scale scores for all body mass index (BMI) categories. (A) Entire cohort. (B) Degenerative cohort. (C) Isthmic cohort.

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    Figure 3

    Oswestry Disability Index scores for all body mass index (BMI) categories. (A) Entire cohort. (B) Degenerative cohort. (C) Isthmic cohort.

Tables

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    Table 1

    Patient and characteristics and surgical outcomes (N = 86).

    Characteristic n (%)
    Sex
     Female50 (58.1%)
     Male36 (41.9%)
    BMI
     <3040 (46.5%)
     30–34.925 (29.1%)
     35–39.915 (17.4%)
     ≥406 (7.0%)
     Mean ± SD30.63 ± 6.99
    Surgical Approach and BMI
     TLIF 
      <3021 (56.8%)
      30–34.99 (24.3%)
      35–39.96 (16.2%)
      ≥401 (2.7%)
      Mean ± SD28.55 ± 6.75
     LLIF 
      <309 (25.7%)
      30–34.914 (40.0%)
      35–39.98 (22.9%)
      ≥404 (11.4%)
      Mean ± SD33.63 ± 5.97
     ALIF 
      <307 (70%)
      30–34.91 (10%)
      35–39.91 (10%)
      ≥401 (10%)
      Mean ± SD28.53 ± 9.02
     OLIF
      <300
      30–34.92 (100%)
      35–39.90
      ≥400
      Mean ± SD32.85 ± 1.06
     Multi-approach 
      <303 (75%)
      30–34.91 (25%)
      35–39.90
      ≥400
      Mean ± SD28.85 ± 3.44
    Prior Lumbar Fusion
     Yes3 (3.5%)
     No83 (96.5%)
    History of Degenerative Disk Disease
     Yes8 (9.3%)
     No78 (90.7%)
    Type of Surgery
     TLIF37 (43.0%)
     LLIF33 (38.4%)
     ALIF10 (11.6%)
     OLIF2 (2.3%)
     Multiple4 (4.7%)
    Segment Level
     L3–49 (10.5%)
     L4–544 (51.2%)
     L5–S114 (16.3%)
     Multilevel19 (22.1%)
    Spondylolisthesis
     Grade 156 (73.7%)
     Grade 220 (26.3%)
     Grade 30
     Grade 40
     Grade 50
    VAS
     0, none8 (9.3%)
     1–3, mild9 (10.5%)
     4–6, moderate23 (26.7%)
     7–10, severe46 (53.5%)
     Mean ± SD5.85 ± 2.83
    ODI
     0–20, minimal6 (7.0%)
     21–40, moderate18 (20.9%)
     41–60, severe46 (53.5%)
     61–80, crippled16 (18.6%)
     81–100, bedbound0
     Mean ± SD47.81 ± 16.32
    • Abbreviations: ALIF, anterior lumbar interbody fusion; BMI, body mass index; LLIF, lateral lumbar interbody fusion; ODI, Oswestry Disability Index; TLIF, transforaminal lumbar interbody fusion; VAS, visual analog scale.

    • Note: Data presented as n (%) unless otherwise noted.

    • View popup
    Table 2

    Primary outcomes for the entire cohort (N = 86).

    ScaleBaseline12-Month Follow-UpMean ChangeMCID P a
    VAS5.93.82.1b 2<0.001
    ODI47.231.515.6b 13<0.001
    • Abbreviations: MCID, minimal clinically important difference; ODI, Oswestry Disability Index; VAS, visual analog scale.

    • ↵a Dependent t test.

    • ↵b MCID.

    • View popup
    Table 3

    VAS and ODI mean change from baseline to 12 months between BMI categories (N = 86).

    ScaleBMIMCID P a
    <30 (n = 39)30–34.9 (n = 25)35–39.9 (n = 16)>40 (n = 6)
    VAS mean change1.81.72.5b 2.5b 20.93
    ODI mean change19.0b 12.815.3b 7.2130.31
    • Abbreviations: ANOVA, analysis of variance; BMI, body mass index ; MCID, minimal clinically important difference; ODI, Oswestry Disability Index; VAS, visual analog scale.

    • ↵a One-way ANOVA.

    • ↵b Met MCID.

    • View popup
    Table 4

    Mean change in VAS and ODI scores for each BMI category.

    BMI CategoryOutcome MeasureBaseline12-Month Follow-UpMean ChangeMCID P
    <30 (n = 39)VAS5.293.661.6320.07
    ODI44.4225.3519.07a 130.003
    30–34.9 (n = 25)VAS6.034.311.7220.03
    ODI45.6032.7612.84130.003
    35–39.9 (n = 16)VAS5.142.572.57a 20.48
    ODI54.8342.0612.7713<0.001
    >40 (n = 6)VAS7.405.002.40a 20.06
    ODI57.2050.007.20130.12
    • Abbreviations: BMI, body mass index ; MCID, minimal clinically important distance; ODI, Oswestry Disability Index; VAS, visual analog scale.

    • ↵a Met MCID.

    • View popup
    Table 5

    Patient characteristics for the type of spondylolisthesis.

    Characteristics n (%)
    Type of spondylolisthesis 
     Degenerative58 (67.4%)
     Isthmic28 (32.6%)
    BMI category, degenerative 
     <3029 (50%)
     30–34.916 (27.6%)
     35–39.99 (15.5%)
     ≥404 (6.9%)
    BMI category, isthmic 
     <3011 (39.3%)
     30–34.99 (32.1%)
     35–39.96 (21.4%)
     ≥402 (7.2%)
     Yes3 (3.6%)
     No83 (96.5%)
    • Abbreviation: BMI, body mass index.

    • View popup
    Table 6

    VAS and ODI mean change from baseline to 12 months between BMI categories for the degenerative cohort.

    ScaleBMIMCID P a
    <30 (n = 39) 30–34.9 (n = 25)35–39.9 (n = 16)>40 (n = 6)
    VAS mean change2.2b 2.7b 0.883.75b 20.70
    ODI mean change28.74b 21.81b 31.67b 12.20130.37
    • Abbreviations: ANOVA, analysis of variance; BMI, body mass index ; MCID, minimal clinically important difference; ODI, Oswestry Disability Index; VAS, visual analog scale.

    • ↵a One-way ANOVA.

    • ↵b Met MCID.

    • View popup
    Table 7

    VAS and ODI mean change from baseline to 12 months between BMI categories for the isthmic cohort.

    ScaleBMIMCID P a
    <30 (n = 39)30–34.9 (n = 25)35–39.9 (n = 16)>40 (n = 6)
    VAS mean change1.631.220.831.520.99
    ODI mean change17.33b 13.23b 12.85−4.0130.59
    • Abbreviations: BMI, body mass index ; MCID, minimal clinically important difference; ODI, Oswestry Disability Index; VAS, visual analog scale.

    • ↵a One-way ANOVA.

    • ↵b Met MCID.

    • View popup
    Table 8

    Return to the operating room, imaging modality, and surgical approach distribution.

    Variable n (%)
    Return to OR 
     Yes8 (9.3%)
     No78 (90.7%)
    Imaging used 
     Radiography79 (91.0%)
     Computed tomography55 (64.0%)
     Magnetic resonance imaging9 (10.5%)
    Surgical approach for patients who returned to OR 
     LLIF4 (50%)
     TLIF3 (37.5%)
     ALIF1 (12.5%)
    BMI, mean ± SD 
     Returned to OR34.9 ± 5.07
     No return to OR30.1 ± 6.89
    • Abbreviations: ALIF, anterior lumbar interbody fusion; BMI, body mass index; LLIF, lateral lumbar interbody fusion; OR, operating room; TLIF, transforaminal lumbar interbody fusion.

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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Effects of Body Mass Index on Spondylolisthesis Surgery and Associated Patient-Reported Outcomes: A Retrospective Review
Rafael Garcia, Kari Odland, Jonathan Sembrano
International Journal of Spine Surgery Apr 2025, 8752; DOI: 10.14444/8752

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Effects of Body Mass Index on Spondylolisthesis Surgery and Associated Patient-Reported Outcomes: A Retrospective Review
Rafael Garcia, Kari Odland, Jonathan Sembrano
International Journal of Spine Surgery Apr 2025, 8752; DOI: 10.14444/8752
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