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Research ArticleLumbar Spine

Recombinant Human Bone Morphogenetic Protein–2 Improves Spine Fusion in a Vitamin D–Deficient Rat Model

VIKAS V. PATEL, ZACHARY R. WUTHRICH, ALICIA ORTEGA, VIRGINIA L. FERGUSON and EMILY M. LINDLEY
International Journal of Spine Surgery October 2020, 14 (5) 694-705; DOI: https://doi.org/10.14444/7101
VIKAS V. PATEL
1Department of Orthopedics, Divisions of Spine Surgery and Research, University of Colorado Anschutz Medical Campus, Aurora, Colorado
MD
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ZACHARY R. WUTHRICH
1Department of Orthopedics, Divisions of Spine Surgery and Research, University of Colorado Anschutz Medical Campus, Aurora, Colorado
BS
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ALICIA ORTEGA
2Department of Mechanical Engineering, University of Colorado Boulder, Boulder, Colorado
PhD
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VIRGINIA L. FERGUSON
2Department of Mechanical Engineering, University of Colorado Boulder, Boulder, Colorado
PhD
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EMILY M. LINDLEY
1Department of Orthopedics, Divisions of Spine Surgery and Research, University of Colorado Anschutz Medical Campus, Aurora, Colorado
PhD
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Article Information

vol. 14 no. 5 694-705
DOI 
https://doi.org/10.14444/7101
PubMed 
33077435

Published By 
International Journal of Spine Surgery
Online ISSN 
2211-4599
History 
  • Published online November 12, 2020.

Article Versions

  • Latest version (October 19, 2020 - 09:29).
  • You are viewing the most recent version of this article.
Copyright & Usage 
This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery. Copyright © 2020 ISASS.

Author Information

  1. VIKAS V. PATEL, MD1,
  2. ZACHARY R. WUTHRICH, BS1,
  3. ALICIA ORTEGA, PhD2,
  4. VIRGINIA L. FERGUSON, PhD2 and
  5. EMILY M. LINDLEY, PhD1
  1. 1Department of Orthopedics, Divisions of Spine Surgery and Research, University of Colorado Anschutz Medical Campus, Aurora, Colorado
  2. 2Department of Mechanical Engineering, University of Colorado Boulder, Boulder, Colorado
  1. Corresponding Author:
    Emily M. Lindley, PhD, Department of Orthopedics, University of Colorado Anschutz Medical Campus, 13001 E. 17th Place, Aurora, CO 80045. Phone: (303) 724-0239; Email: emily.lindley{at}cuanschutz.edu.
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1 Oct 2020
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Recombinant Human Bone Morphogenetic Protein–2 Improves Spine Fusion in a Vitamin D–Deficient Rat Model
VIKAS V. PATEL, ZACHARY R. WUTHRICH, ALICIA ORTEGA, VIRGINIA L. FERGUSON, EMILY M. LINDLEY
International Journal of Spine Surgery Oct 2020, 14 (5) 694-705; DOI: 10.14444/7101

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Recombinant Human Bone Morphogenetic Protein–2 Improves Spine Fusion in a Vitamin D–Deficient Rat Model
VIKAS V. PATEL, ZACHARY R. WUTHRICH, ALICIA ORTEGA, VIRGINIA L. FERGUSON, EMILY M. LINDLEY
International Journal of Spine Surgery Oct 2020, 14 (5) 694-705; DOI: 10.14444/7101
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  • Recovery Trajectories After Lumbar Fusion Stratified by Baseline Patient-Reported Outcomes Measurement Information System Physical Function Disability Levels
  • Safety and Viability of Anterior Lumbar Interbody Fusion in Complex Revision Lumbar Spine Surgeries: Insights From a Case Series of 135 Patients on Transforaminal Lumbar Interbody Fusion/Posterior Lumbar Interbody Fusion Cage Removal
  • Effects of Body Mass Index on Spondylolisthesis Surgery and Associated Patient-Reported Outcomes: A Retrospective Review
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Keywords

  • vitamin D
  • lumbar spine
  • fusion
  • rat model
  • rhBMP-2
  • micro-CT
  • allograft

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