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Research ArticleLumbar Spine

Anterior Lumbar Interbody Fusion With Cement Augmentation Without Posterior Fixation to Treat Isthmic Spondylolisthesis in an Osteopenic Patient—A Surgical Technique

Mathew Cyriac, Justin Kyhos, Uchechi Iweala, Danny Lee, Matthew Mantell and Joseph R. O'Brien
International Journal of Spine Surgery June 2018, 5037; DOI: https://doi.org/10.14444/5037
Mathew Cyriac
1Tulane University, New Orleans, Louisiana
MD, MBA
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Justin Kyhos
2Northwestern University, Chicago, Illinois
MD
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Uchechi Iweala
3George Washington University, Washington DC
MD, MBA
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Danny Lee
3George Washington University, Washington DC
BS
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Matthew Mantell
3George Washington University, Washington DC
MD
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Joseph R. O'Brien
4Washington Spine and Scoliosis Clinic, OrthoBethesda, Bethesda, Maryland
MD, MPH
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ABSTRACT

Background Anterior lumbar interbody fusion (ALIF) has been well established as an effective surgical intervention for chronic back pain due to osteoporotic vertebral collapse. Historically, ALIF has consisted of an anterior approach to disc height restoration with a subsequent posterior pedicle screw fixation. Although the applications of cement augmentation with posterior fixation have been previously reported, treatment of patients with both isthmic spondylolisthesis and decreased bone mineral density using a stand-alone ALIF is controversial because of concerns for decreased fusion rates and increased subsidence risk, respectively. We report a case of stand-alone ALIF used to treat a low-grade isthmic spondylolisthesis in the setting of idiopathic thoraco-lumbar scoliosis in a patient with secondary degenerative changes and discuss the benefits of this surgical technique in a patient with several comorbidities.

Methods An osteopenic 66-year-old woman with multiple medical comorbidities and 2 years of left radicular leg pain was found to have a Myerding grade I isthmic spondylolisthesis in the setting of idiopathic thoraco-lumbar scoliosis with secondary changes. The patient underwent an L5-S1 stand-alone ALIF with anterior cement augmentation without posterior pedicle screw fixation.

Results The patient experienced immediate relief of radicular leg pain postoperatively and had an uneventful course. At 2 years follow-up, she remained symptom free, and radiographs showed excellent fusion and maintenance of intervertebral disc height.

Conclusions The use of stand-alone ALIF with anterior cement augmentation of the vertebral bodies is a surgical technique that could produce excellent improvement in patients with low-grade isthmic spondylolisthesis in the setting of osteopenia. The use of the all-anterior approach in similar patients with multiple medical comorbidities can also be a useful technique, as it decreases associated morbidity of surgery and complication risks associated with prolonged operative times.

  • anterior lumbar interbody fusion
  • osteopenia
  • osteoporosis
  • anterior cement augmentation
  • isthmic spondylolisthesis

Footnotes

  • Disclosures and COI: No funds were received in support of this work. The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper. This study was approved by the Institutional Review Board of George Washington University Hospital in Washington, DC.

  • ©International Society for the Advancement of Spine Surgery
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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Anterior Lumbar Interbody Fusion With Cement Augmentation Without Posterior Fixation to Treat Isthmic Spondylolisthesis in an Osteopenic Patient—A Surgical Technique
Mathew Cyriac, Justin Kyhos, Uchechi Iweala, Danny Lee, Matthew Mantell, Joseph R. O'Brien
International Journal of Spine Surgery Jun 2018, 5037; DOI: 10.14444/5037

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Anterior Lumbar Interbody Fusion With Cement Augmentation Without Posterior Fixation to Treat Isthmic Spondylolisthesis in an Osteopenic Patient—A Surgical Technique
Mathew Cyriac, Justin Kyhos, Uchechi Iweala, Danny Lee, Matthew Mantell, Joseph R. O'Brien
International Journal of Spine Surgery Jun 2018, 5037; DOI: 10.14444/5037
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  • Letter to the Editor Regarding Anterior Lumbar Interbody Fusion With Cement Augmentation Without Posterior Fixation to Treat Isthmic Spondylolisthesis in an Osteopenic Patient--A Surgical Technique, by Cyriac et al.
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  • Comparison of Stand-Alone Anterior Lumbar Interbody Fusion, 360° Anterior Lumbar Interbody Fusion, and Arthroplasty for Recurrent Lumbar Disc Herniation: Focus on Nerve Decompression and Painful Spinal Instability Resolution
  • Recovery Trajectories After Lumbar Fusion Stratified by Baseline Patient-Reported Outcomes Measurement Information System Physical Function Disability Levels
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Keywords

  • anterior lumbar interbody fusion
  • osteopenia
  • osteoporosis
  • anterior cement augmentation
  • isthmic spondylolisthesis

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