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Research ArticleMinimally Invasive Surgery

Comparative Radiographic Analyses and Clinical Outcomes Between O-Arm Navigated and Fluoroscopic-Guided Minimally Invasive Transforaminal Lumbar Interbody Fusion

Weerasak Singhatanadgige, Phattareeya Pholprajug, Kittisak Songthong, Wicharn Yingsakmongkol, Chanonta Triganjananun, Vit Kotheeranurak and Worawat Limthongkul
International Journal of Spine Surgery February 2022, 8183; DOI: https://doi.org/10.14444/8183
Weerasak Singhatanadgige
1 Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
2 Center of Excellence in Biomechanics and Innovative Spine Surgery, Chulalongkorn University, Bangkok, Thailand
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Phattareeya Pholprajug
1 Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
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Kittisak Songthong
1 Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
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Wicharn Yingsakmongkol
1 Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
2 Center of Excellence in Biomechanics and Innovative Spine Surgery, Chulalongkorn University, Bangkok, Thailand
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Chanonta Triganjananun
1 Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
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Vit Kotheeranurak
3 Department of Orthopedics, Queen Savang Vadhana Memorial Hospital, Sriracha, Chonburi, Thailand
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Worawat Limthongkul
1 Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
2 Center of Excellence in Biomechanics and Innovative Spine Surgery, Chulalongkorn University, Bangkok, Thailand
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  • Article
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  • Figure 1
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    Figure 1

    Postoperative thin-slice computed tomography performed at 12 months. (A) PW = pedicle width, (B) b = body length, SL = screw length (% SD = [SL/b] × 100), and C = angle of medial convergence.

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    Figure 2

    Cage subsidence grading (0–3).

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    Figure 3

    The grading system (Gertzbein). (A) Grade 0: screw within pedicle, (B) Grade 1: screw thread breach of pedicle <2 mm, (C) Grade 2: significant breach 2–4 mm, and (D) Grade 3: significant breach <4 mm.

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    Figure 4

    Facet joint violation. (A) Intra-articular pedicle screw that penetrates the facet joint transversely, interposed between the superior and inferior facet at the cephalad level. (B) Screw did not transverse the facet joint; extra-articular screw.

Tables

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    Table 1

    Patient demographic data.

    Patient DataFLUO MIS-TLIF (N = 61)NAV MIS-TLIF (N = 36) P Value
    Age65.67 ± 9.2365.89 ± 9.690.913
    Sex
     Female41 (67.2%)23 (63.9%)0.825
     Male20 (32.8%)13 (36.1%)0.825
    Body mass index25.22 ± 2.9624.86 ± 3.310.660
    Diagnosis
     Spondylolisthesis24 (39.3%)22 (61.1%)0.058
     Spinal stenosis7 (11.5%)2 (5.6%)0.477
     Spinal canal stenosis17 (27.9%)8 (22.2%)0.634
     Herniated nucleus pulposus12 (19.7%)3 (8.3%)0.159
     Degenerative scoliosis0 (0%)1 (2.8%)0.371
     Degenerative disc disease1 (1.6%)0 (0%)1.000
    Level
     L3-43 (4.9%)2 (5.6%)0.745
     L3-57 (11.5%)6 (16.6%)0.703
     L4-538 (62.3%)20 (55.6%)0.612
     L4-S16 (9.8%)4 (11.1%)0.800
     L5-S17 (11.5%)4 (11.1%)0.258
    Blood loss (mL)171.03 ± 157.75124.44 ± 147.420.157
    Operative time (min)173.91 ± 52.93163.64 ± 52.060.360
    Length of stay (d)5.2 ± 2.415.03 ± 2.460.751
    Radiation dose (mGy)38.26 ± 5.6611.49±2.13< 0.05
    • Data presented as mean ± SD or n (%).

    • FLUO, fluoroscopic-guided; MIS-TILF, minimally invasive transforaminal lumbar interbody fusion; NAV, 3-dimensional computer navigation.

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    Table 2

    Comparison of radiographic outcomes between the 2 groups.

    Raidographic ParametersFLUO MIS-TLIF (N = 61)NAV MIS-TLIF (N = 36) P Value
    Screw-to-pedicle ratio0.7 ± 0.130.66 ± 0.090.079
    % Screw depth85.18 ± 7.5489.04 ± 6.070.011a
    Angle of medial convergence18.44 ± 11.5527.7±3.93<0.001a
    % Screw penetration(n = 270)(n = 172)
     Anterior47 (17.4%)16 (9.7%)0.027a
     Lateral5 (1.9%)4 (2.4%)0.684
     Medial10 (3.7%)0 (0%)0.012a
     Superior1 (0.4%)1 (0.6%)0.724
    Cage size23.61 ± 1.9324.78 ± 1.740.003a
    Cage location
     Anterior24 (44.4%)30 (55.6%)0.471
     Posterior49 (74.2%)17 (25.8%)0.471
    Cage subsidence (<2 mm)39 (63.9%)23 (63.9%)0.996
    Fusion55 (90.2%)33 (91.7%)0.481
    • Data presented as mean ± SD or n (%).

    • aStatistically significant (P < 0.05)

    • FLOU, fluoroscopic-guided; MIS-TILF, minimally invasive transforaminal lumbar interbody fusion; NAV, 3-dimensional computer navigation.

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    Table 3

    Comparison of clinical results over time between the 2 groups.

    Clinical ScoresFLUO MIS-TLIFNAV MIS-TLIF P Value
    Mean ± SEMean ± SE
    VAS of back score
     Pre-OP6.48 ± 0.437.14 ± 0.450.312
     1 mo1.13 ± 0.230.78 ± 0.260.325
     3 mo0.72 ± 0.20.48 ± 0.220.454
     6 mo0.83 ± 0.250.43 ± 0.230.361
     1 y0.63 ± 0.20.11 ± 0.110.025a
    VAS leg score
     Pre-OP6.9 ± 0.387.56 ± 0.390.261
     1 mo1.32 ± 0.271.14 ± 0.230.649
     3 mo1.11 ± 0.290.58 ± 0.210.143
     6 mo1.07 ± 0.290.13 ± 0.12< 0.001a
     1 y0.78 ± 0.260.11 ± 0.110.019a
    ODI
     Pre-OP49.07 ± 2.0653.83 ± 1.910.123
     1 mo11.86 ± 1.7411.69 ± 1.890.949
     3 mo8.26 ± 24.39 ± 1.730.200
     6 mo6.86 ± 1.860.67 ± 0.670.003a
     1 y5.21 ± 1.690.49 ± 0.490.009a
    Satisfaction score
     1 mo8.81 ± 0.239.31 ± 0.140.068
     3 mo8.82 ± 0.239.42 ± 0.160.081
     6 mo8.93 ± 0.239.35 ± 0.150.302
     1 y9.16 ± 0.189.39 ± 0.160.495
    • aStatistically significant (P < 0.05).

    • FLUO, fluoroscopic-guided; MIS-TILF, minimally invasive transforaminal lumbar interbody fusion; NAV, 3-dimensional computer navigation.

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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
Vol. 19, Issue S2
1 Apr 2025
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Comparative Radiographic Analyses and Clinical Outcomes Between O-Arm Navigated and Fluoroscopic-Guided Minimally Invasive Transforaminal Lumbar Interbody Fusion
Weerasak Singhatanadgige, Phattareeya Pholprajug, Kittisak Songthong, Wicharn Yingsakmongkol, Chanonta Triganjananun, Vit Kotheeranurak, Worawat Limthongkul
International Journal of Spine Surgery Feb 2022, 8183; DOI: 10.14444/8183

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Comparative Radiographic Analyses and Clinical Outcomes Between O-Arm Navigated and Fluoroscopic-Guided Minimally Invasive Transforaminal Lumbar Interbody Fusion
Weerasak Singhatanadgige, Phattareeya Pholprajug, Kittisak Songthong, Wicharn Yingsakmongkol, Chanonta Triganjananun, Vit Kotheeranurak, Worawat Limthongkul
International Journal of Spine Surgery Feb 2022, 8183; DOI: 10.14444/8183
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  • A Spine Surgeon’s Learning Curve With the Minimally Invasive L5 to S1 Lateral ALIF Surgical Approach: Perioperative Outcomes and Technical Considerations
  • Fully Navigated Single-Position Prone Lateral Lumbar Interbody Fusion: A Detailed Technical Report and Description of 15 Cases
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Keywords

  • MIS-TLIF
  • computer-3D navigation
  • screw accuracy
  • clinical outcome
  • radiographic analysis
  • lumbosacral degenerative disease
  • facet joint violation
  • screw convergence
  • screw depth

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