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Research ArticleLumbar Spine

Allogeneic Disc Progenitor Cells Safely Increase Disc Volume and Improve Pain, Disability, and Quality of Life in Patients With Lumbar Disc Degeneration—Results of an FDA-Approved Biologic Therapy Randomized Clinical Trial

Matthew F. Gornet, Douglas P. Beall, Timothy T. Davis, Domagoj Coric, Michael LaBagnara, Angela Krull, Michael J. DePalma, Patrick C. Hsieh, Srinivas Mallempati, Francine W. Schranck, Colleen Kelly and Kevin T. Foley
International Journal of Spine Surgery June 2024, 8609; DOI: https://doi.org/10.14444/8609
Matthew F. Gornet
1 The Orthopedic Center of St. Louis, St. Louis, MO, USA
MD
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Douglas P. Beall
2 Clinical Radiology of Oklahoma, Edmond, OK, USA
MD
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Timothy T. Davis
3 Source Health Care, Santa Monica, CA, USA
MD
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Domagoj Coric
4 Carolinas Medical Center/Carolina Neurosurgery & Spine Associates, Charlotte, NC, USA
MD
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Michael LaBagnara
5 Semmes-Murphey Clinic and Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN, USA
MD
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Angela Krull
6 SMART Clinic, Draper, UT, USA
MD
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Michael J. DePalma
7 Virginia iSpine Physicians/Virginia Spine Research Institute, Richmond, VA, USA
MD
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Patrick C. Hsieh
8 Los Angeles—USC Health Care Center, Los Angeles, CA, USA
MD, MS
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Srinivas Mallempati
9 Alabama Clinical Therapeutics, Birmingham, AL, USA
MD
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Francine W. Schranck
10 SPIRITT Research, St. Louis, MO, USA
BSN
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Colleen Kelly
11 Kelly Statistical Consulting, Carlsbad, CA, USA
PʜD
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Kevin T. Foley
5 Semmes-Murphey Clinic and Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN, USA
MD, FACS
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  • For correspondence: kfoley@semmes-murphey.com
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Article Information

8609
DOI 
https://doi.org/10.14444/8609
PubMed 
38925869

Published By 
International Journal of Spine Surgery
Online ISSN 
2211-4599
History 
  • Published online June 26, 2024.

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  • You are currently viewing a Latest version of this article (June 26, 2024 - 07:55).
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Copyright & Usage 
This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery. Copyright © 2024 ISASS. To see more or order reprints or permissions, see http://ijssurgery.com.

Author Information

  1. Matthew F. Gornet, MD1,
  2. Douglas P. Beall, MD2,
  3. Timothy T. Davis, MD3,
  4. Domagoj Coric, MD4,
  5. Michael LaBagnara, MD5,
  6. Angela Krull, MD6,
  7. Michael J. DePalma, MD7,
  8. Patrick C. Hsieh, MD, MS8,
  9. Srinivas Mallempati, MD9,
  10. Francine W. Schranck, BSN10,
  11. Colleen Kelly, PʜD11 and
  12. Kevin T. Foley, MD, FACS5⇑
  1. 1 The Orthopedic Center of St. Louis, St. Louis, MO, USA
  2. 2 Clinical Radiology of Oklahoma, Edmond, OK, USA
  3. 3 Source Health Care, Santa Monica, CA, USA
  4. 4 Carolinas Medical Center/Carolina Neurosurgery & Spine Associates, Charlotte, NC, USA
  5. 5 Semmes-Murphey Clinic and Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN, USA
  6. 6 SMART Clinic, Draper, UT, USA
  7. 7 Virginia iSpine Physicians/Virginia Spine Research Institute, Richmond, VA, USA
  8. 8 Los Angeles—USC Health Care Center, Los Angeles, CA, USA
  9. 9 Alabama Clinical Therapeutics, Birmingham, AL, USA
  10. 10 SPIRITT Research, St. Louis, MO, USA
  11. 11 Kelly Statistical Consulting, Carlsbad, CA, USA
  1. Correspondence to Kevin T. Foley, Semmes-Murphey Clinic & Department of Neurosurgery, University of Tennessee Health Science Center, 6325 Humphreys Blvd, Memphis, TN 38120, USA; kfoley{at}semmes-murphey.com
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International Journal of Spine Surgery: 19 (S2)
International Journal of Spine Surgery
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Allogeneic Disc Progenitor Cells Safely Increase Disc Volume and Improve Pain, Disability, and Quality of Life in Patients With Lumbar Disc Degeneration—Results of an FDA-Approved Biologic Therapy Randomized Clinical Trial
Matthew F. Gornet, Douglas P. Beall, Timothy T. Davis, Domagoj Coric, Michael LaBagnara, Angela Krull, Michael J. DePalma, Patrick C. Hsieh, Srinivas Mallempati, Francine W. Schranck, Colleen Kelly, Kevin T. Foley
International Journal of Spine Surgery Jun 2024, 8609; DOI: 10.14444/8609

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Allogeneic Disc Progenitor Cells Safely Increase Disc Volume and Improve Pain, Disability, and Quality of Life in Patients With Lumbar Disc Degeneration—Results of an FDA-Approved Biologic Therapy Randomized Clinical Trial
Matthew F. Gornet, Douglas P. Beall, Timothy T. Davis, Domagoj Coric, Michael LaBagnara, Angela Krull, Michael J. DePalma, Patrick C. Hsieh, Srinivas Mallempati, Francine W. Schranck, Colleen Kelly, Kevin T. Foley
International Journal of Spine Surgery Jun 2024, 8609; DOI: 10.14444/8609
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