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Research ArticleTotal Disc Replacement

Segmental Motion of Cervical Arthroplasty Leads to Decreased Adjacent-Level Degeneration: Analysis of the 7-Year Postoperative Results of a Multicenter Randomized Controlled Trial

Jeffrey M. Spivak, Jack E. Zigler, Travis Philipp, Michael Janssen, Bruce Darden and Kris Radcliff
International Journal of Spine Surgery February 2022, 8187; DOI: https://doi.org/10.14444/8187
Jeffrey M. Spivak
1 NYU Langone Orthopedic Hospital, New York, NY, USA
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Jack E. Zigler
2 Texas Back Institute, Plano, TX, USA
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Travis Philipp
3 Oregon Health and Science University, Sam Jackson Hall, Portland, OR, USA
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Michael Janssen
4 Center for Spinal Disorders, Center for Spinal Disorders, Thornton, CO, USA
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Bruce Darden
5 Ortho Carolina Spine Center, Charlotte, NC, USA
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Kris Radcliff
6 Rothman Orthopedics, Philadelphia, PA, USA
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    Figure 1

    Randomization and follow-up flow chart. “Withdrew” indicates that the patient signed the informed consent but later withdrew from the study. “Missed follow-up” means the patient was lost to follow-up. ACDF, anterior cervical discectomy and fusion.

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    Figure 2

    Example of C6-7 cervical disc replacement vs anterior cervical discectomy and fusion.

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    Figure 3

    Example of Kellgren-Lawrence classification for grading disc degeneration originally described in 1957.

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    Figure 4

    Rate of progressive adjacent- level degeneration between anterior cervical discectomy and fusion (ACDF) and cervical artificial disc replacement (C-ADR).

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    Figure 5

    Rate of progressive radiographic adjacent-level disease by final cervical artificial disc replacement (C-ADR) range of motion (ROM) group (includes the anterior cervical discectomy and fusion [ACDF] patients, which represents a 0° ROM group).

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    Figure 6

    Magnitude of progression of adjacent-level disease by range of motion group.

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    Figure 7

    Rate of severe progression of adjacent-level disease by range of motion group.

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International Journal of Spine Surgery
Vol. 19, Issue 3
1 Jun 2025
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Segmental Motion of Cervical Arthroplasty Leads to Decreased Adjacent-Level Degeneration: Analysis of the 7-Year Postoperative Results of a Multicenter Randomized Controlled Trial
Jeffrey M. Spivak, Jack E. Zigler, Travis Philipp, Michael Janssen, Bruce Darden, Kris Radcliff
International Journal of Spine Surgery Feb 2022, 8187; DOI: 10.14444/8187

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Segmental Motion of Cervical Arthroplasty Leads to Decreased Adjacent-Level Degeneration: Analysis of the 7-Year Postoperative Results of a Multicenter Randomized Controlled Trial
Jeffrey M. Spivak, Jack E. Zigler, Travis Philipp, Michael Janssen, Bruce Darden, Kris Radcliff
International Journal of Spine Surgery Feb 2022, 8187; DOI: 10.14444/8187
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More in this TOC Section

  • Single-Level Total Disc Replacement: Mid- to Long-Term Outcomes
  • Single-Level Total Disc Replacement: Index-Level and Adjacent-Level Revision Surgery Incidence, Characteristics, and Outcomes
  • Anterior Cervical Foraminotomy for Radiculopathy After Cervical Artificial Disc Replacement: Technique Description and Case Report
Show more Total Disc Replacement

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Keywords

  • cervical arthroplasty
  • Adjacent segment degeneration
  • disc replacement

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